Evidence map›Paper›PMID 36160482›Full record

ArticleCase reports in ophthalmology

Intrastromal Antibiotic Injection in Polymicrobial Keratitis: Case Report and Literature Review.

Clara M Pak, Daniel E Savage, Ronald Plotnik, Rachel A F Wozniak

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Case reports in ophthalmology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Intrastromal antimicrobial injections in microbial keratitis: Current evidence and clinical perspectives.Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Clara M PakDepartment of Ophthalmology, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA.
Daniel E SavageDepartment of Ophthalmology, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA.
Ronald PlotnikDepartment of Ophthalmology, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA.
Rachel A F WozniakDepartment of Ophthalmology, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacterial keratitis (corneal infection) caused by more than one organism is rare and exceedingly difficult to treat due to variable antibiotic susceptibilities. Intrastromal injections of antibiotics may be necessary to achieve higher drug concentrations at the site of infection, particularly in the case of deep stromal disease refractory to topical therapy. However, while this approach is increasingly used for fungal keratitis, there is a paucity of the literature regarding the use of intrastromal antibiotics bacterial keratitis. In the current case, an 86-year-old patient presented with a left corneal ulcer with corresponding microbiologic cultures positive for

Indexed as

Case reportIntrastromal antibioticsIntrastromal injectionsPolymicrobial keratitis

Identifiers

PMID36160482
PMCPMC9386406

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.