Evidence map›Paper›PMID 36160175›Full record

ArticleFrontiers in medicine2022

COVID-19 vaccination reduces mortality in patients on maintenance hemodialysis.

Leszek Tylicki, Bogdan Biedunkiewicz, Ewelina Puchalska-Reglińska, Ryszard Gellert, Michel Burnier, Jacek Wolf, Alicja Dȩbska-Ślizień

Abstract read
In one paragraph

Article in Frontiers in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Leszek TylickiDepartment of Nephrology, Transplantology and Internal Medicine, Medical University of Gdansk, Gdańsk, Poland.
Bogdan BiedunkiewiczDepartment of Nephrology, Transplantology and Internal Medicine, Medical University of Gdansk, Gdańsk, Poland.
Ewelina Puchalska-ReglińskaDialysis Unit, 7th Naval Hospital in Gdansk, Gdańsk, Poland.
Ryszard GellertDepartment of Nephrology and Internal Medicine, Medical Center for Postgraduate Education, Warsaw, Poland.
Michel BurnierFaculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland.
Jacek WolfTranslational Medicine Centre, Medical University of Gdańsk, Gdańsk, Poland.
Alicja Dȩbska-ŚlizieńDepartment of Nephrology, Transplantology and Internal Medicine, Medical University of Gdansk, Gdańsk, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients with chronic kidney disease on maintenance hemodialysis (HD) have a very high risk of death in the course of COVID-19. The aim of the study was to assess the effectiveness of COVID-19 vaccination to reduce the incidence of COVID-19 and the fatality rate in HD patients. A retrospective registry-based cohort study was performed in all HD adult patients in the Pomeranian Voivodeship. Vaccinations were carried out from January to April 2021 with mRNA vaccines, either BNT162b2 or mRNA-1273 with two-dose schedule. In the first analysis (2nd pandemic wave), 1,160 unvaccinated patients were included (59.7% males, 25.7% diabetic). In the second analysis (4th pandemic wave), 1,131 (59.4% male, 30.7% diabetic) individuals were included, 1,042 (92.13%) were fully vaccinated. Three hundred and fifteen HD patients (27.2%) were COVID-19 positive during the 2nd wave, and 6.9% (78/1,131) during the 4th wave. Within the fully vaccinated patients of the 4th wave, 60 were COVID-19 positive, 5.8 vs. 20.2% of unvaccinated COVID-19 positive patients in 2nd wave, respectively. COVID-19 incidence rate ratio (IRR) was 0.21 (4th wave-vaccinated vs. 2nd wave-unvaccinated) indicating a 79% reduction. The IRR between vaccinated and unvaccinated patients of the 4th wave was 0.28 in favor of vaccinated patients with 72% reduction. In the 2nd wave, 93 patients died as a result of COVID-19 (fatality rate: 29.5%). The fatality rate of fully vaccinated patients during the 4th wave was 6.7% (

Indexed as

COVID-19fatality rateincidencemaintenance dialysisvaccination

Identifiers

PMID36160175
PMCPMC9492862

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.