ArticleNoro psikiyatri arsivi2022
The Relationship Between Anti-HCV Screening and Clinical Features of Inpatients in Addiction Center.
Article in Noro psikiyatri arsivi, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: In this study, it was aimed to screen inpatients in the Antalya Ataturk State Hospital Alcohol and Substance Addiction Treatment Center (AMATEM) Clinic in terms of anti-hepatitis C virus (anti-HCV) seropositivity and to compare them in terms of sociodemographic data and clinical characteristics. Method: The files of inpatients in the AMATEM Clinic of Ataturk State Hospital between July 2020 - February 2021 were retrospectively scanned and recorded with a semi-structured data form. The collected data was analysed using the SPSS 26.0 program. Independent sample t-test was used for normally distributed numerical variables, Mann-Whitney U test was used for non-normally distributed numerical variables, and chi-square test was used for categorical variables. To examine the relationship between variables showing significant difference and Anti-HCV positivity, binary logistic regression analysis was used. The limit of statistical significance was accepted as p<0.05 for all analyses. Results: Of the 155 patients included in the study, 57.4% were diagnosed with opiate use disorder, 40% with multiple substance use disorder. The rate of multiple substance use, syringe use, syringe sharing, self-mutilation and tattoo/piercing were significantly higher in anti-HCV positive patients (p=0.02, p<0.001, p<0.001, p=0.02, p=0.03 respectively). Patients who were positive for anti-HCV had been using substances for a longer time and were hospitalized more frequently, and the Addiction Profile Index substance abuse subscale scores were higher (p<0.001, p=0.001, p=0.01, respectively). Conclusion: The risk of exposure to HCV in patients with substance use disorder is significantly higher than non-substance user population. It is important to perform anti-HCV screening, especially for people who inject drugs to prevent under-diagnosis of the disease. Considering the risk posed by the use and sharing of syringes, it seems necessary to develop preventive and therapeutic approaches meticulously.
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