Evidence map›Paper›PMID 36159835›Full record

ArticleFrontiers in immunology2022

Delivery of antigen to porcine dendritic cells by fusing antigen with porcine dendritic cells targeting peptide.

Tian Xia, Ning Wang, Yuqing Tang, Yueyi Gao, Chong Gao, Jianhui Hao, Yanping Jiang, Xiaona Wang, Zhifu Shan, Jiaxuan Li and 6 more

Abstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Tian XiaCollege of Veterinary Medicine, Northeast Agricultural University, Harbin, China.
Ning WangCollege of Veterinary Medicine, Northeast Agricultural University, Harbin, China.
Yuqing TangCollege of Veterinary Medicine, Northeast Agricultural University, Harbin, China.
Yueyi GaoDivision of Viral Biologic Testing(I), China Institute of Veterinary Drug Control, Beijing, China.
Chong GaoCollege of Veterinary Medicine, Northeast Agricultural University, Harbin, China.
Jianhui HaoCollege of Veterinary Medicine, Northeast Agricultural University, Harbin, China.
Yanping JiangCollege of Veterinary Medicine, Northeast Agricultural University, Harbin, China.
Xiaona WangCollege of Veterinary Medicine, Northeast Agricultural University, Harbin, China.
Zhifu ShanCollege of Veterinary Medicine, Northeast Agricultural University, Harbin, China.
Jiaxuan LiCollege of Veterinary Medicine, Northeast Agricultural University, Harbin, China.
Han ZhouCollege of Veterinary Medicine, Northeast Agricultural University, Harbin, China.
Wen CuiCollege of Veterinary Medicine, Northeast Agricultural University, Harbin, China.
Xinyuan QiaoCollege of Veterinary Medicine, Northeast Agricultural University, Harbin, China.
Lijie TangCollege of Veterinary Medicine, Northeast Agricultural University, Harbin, China.
Li WangCollege of Veterinary Medicine, Northeast Agricultural University, Harbin, China.
Yijing LiCollege of Veterinary Medicine, Northeast Agricultural University, Harbin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dendritic cells (DCs) are professional antigen-presenting cells that can recognize, capture, and process antigens. Fusing molecules targeting DCs with antigens can effectively improve the efficiency with which antigens are recognized and captured by DCs. This targeting strategy can be used for vaccine development to effectively improve the efficiency of antigen recognition and capture by DCs. The targeting sequence of porcine cytotoxic T-lymphocyte associated protein 4 (CTLA4), which binds porcine DCs, was identified in this study. Recombinant

Indexed as

Dendritic CellsAnimalsB7 AntigensCTLA-4 AntigenCytokinesEpitopesImmunoglobulin AImmunoglobulin GLactobacillusPeptidesSwineB7 AntigensCTLA-4 AntigenCytokinesEpitopesImmunoglobulin AImmunoglobulin GPeptidesCTLA4fusion expressionporcine dendritic cellsrecombinant lactobacillustargeting

Identifiers

PMID36159835
PMCPMC9499840

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.