Evidence map›Paper›PMID 36159666›Full record

ArticleFrontiers in bioengineering and biotechnology2022

Systemically engineering

Susheng Wang, Rui Wang, Xiuyun Zhao, Gaoqiang Ma, Na Liu, Yuqing Zheng, Jun Tan, Gaofu Qi

Abstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Small non-coding RNAMicrobiology spectrum · 2026
    Article
  2. Article
  3. Article
  4. Frontiers in plant science · 2026
    Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Diosgenin producingComputational and structural biotechnology journal · 2025
    Article
  11. Article
  12. Article
  13. Microorganisms · 2023
    Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Susheng WangCollege of Life Science and Technology, Huazhong Agricultural University, Wuhan, Hubei, China.
Rui WangEnshi Tobacco Technology Center, Enshi City, Hubei, China.
Xiuyun ZhaoCollege of Life Science and Technology, Huazhong Agricultural University, Wuhan, Hubei, China.
Gaoqiang MaCollege of Life Science and Technology, Huazhong Agricultural University, Wuhan, Hubei, China.
Na LiuCollege of Life Science and Technology, Huazhong Agricultural University, Wuhan, Hubei, China.
Yuqing ZhengCollege of Life Science and Technology, Huazhong Agricultural University, Wuhan, Hubei, China.
Jun TanEnshi Tobacco Technology Center, Enshi City, Hubei, China.
Gaofu QiCollege of Life Science and Technology, Huazhong Agricultural University, Wuhan, Hubei, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The biosynthesis of antifungal lipopeptides iturin and fengycin has attracted broad interest; however, there is a bottleneck in its low yield in wild strains. Because the key metabolic mechanisms in the lipopeptides synthesis pathway remain unclear, genetic engineering approaches are all ending up with a single or a few gene modifications. The aim of this study is to develop a systematic engineering approach to improve the antifungal activity and biosynthesis of iturin and fengycin in

Indexed as

Bacillus amyloliquefaciensfengyciniturinlipopeptidemetabolic engineering

Identifiers

PMID36159666
PMCPMC9490133

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.