Evidence map›Paper›PMID 36159465›Full record

ArticleFrontiers in nutrition2022

E40 glutenase detoxification capabilities of residual gluten immunogenic peptides in

Gianfranco Mamone, Maria Cristina Comelli, Serena Vitale, Luigia Di Stasio, Katharina Kessler, Ilaria Mottola, Francesco Siano, Linda Cavaletti, Carmen Gianfrani

Abstract read
In one paragraph

Article in Frontiers in nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Gianfranco MamoneInstitute of Food Science, National Research Council of Italy, Avellino, Italy.
Maria Cristina ComelliNemysis Limited, Dublin, Ireland.
Serena VitaleInstitute of Biochemistry and Cell Biology, National Research Council of Italy, Naples, Italy.
Luigia Di StasioInstitute of Food Science, National Research Council of Italy, Avellino, Italy.
Katharina KesslerNemysis Limited, Dublin, Ireland.
Ilaria MottolaInstitute of Biochemistry and Cell Biology, National Research Council of Italy, Naples, Italy.
Francesco SianoInstitute of Food Science, National Research Council of Italy, Avellino, Italy.
Linda CavalettiFondazione Istituto Insubrico Ricerca per la Vita, Varese, Italy.
Carmen GianfraniInstitute of Biochemistry and Cell Biology, National Research Council of Italy, Naples, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gluten degrading enzymes, which are commonly referred to as "glutenases," represent attractive candidates for the development of a pharmacological treatment of gluten related disorders, such as coeliac disease (CeD). Endoprotease-40 (E40), a novel glutenase secreted by the actinomycete

Indexed as

coeliac disease (CeD)Endoprotease 40 (E40)gliadinsgluten immunogenic peptides (GIP)oral enzymatic therapy (OET)

Identifiers

PMID36159465
PMCPMC9493446

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.