Evidence map›Paper›PMID 36159454›Full record

ArticleFrontiers in nutrition2022

Assessment of the neuroprotective potential of d-cycloserine and l-serine in aluminum chloride-induced experimental models of Alzheimer's disease:

Özlem Özdemir Tozlu, Hasan Türkez, Ufuk Okkay, Onur Ceylan, Cemil Bayram, Ahmet Hacımüftüoğlu, Adil Mardinoğlu

Abstract read
In one paragraph

Article in Frontiers in nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Experimental modeling of Alzheimer's disease: Translational lessons from cross-taxon analyses.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Özlem Özdemir TozluDepartment of Molecular Biology and Genetics, Erzurum Technical University, Erzurum, Turkey.
Hasan TürkezDepartment of Medical Biology, Faculty of Medicine, Atatürk University, Erzurum, Turkey.
Ufuk OkkayDepartment of Medical Pharmacology, Faculty of Medicine, Atatürk University, Erzurum, Turkey.
Onur CeylanDepartment of Medical Pathology, Faculty of Medicine, Atatürk University, Erzurum, Turkey.
Cemil BayramDepartment of Medical Pharmacology, Faculty of Medicine, Atatürk University, Erzurum, Turkey.
Ahmet HacımüftüoğluDepartment of Medical Pharmacology, Faculty of Medicine, Atatürk University, Erzurum, Turkey.
Adil MardinoğluScience for Life Laboratory, KTH-Royal Institute of Technology, Stockholm, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alzheimer's disease (AD) is a neurodegenerative disease characterized by the accumulation of amyloid-β (Aβ) plaques and neurofibrillary tangles in the brain accompanied by synaptic dysfunction and neurodegeneration. No effective treatment has been found to slow the progression of the disease. Therapeutic studies using experimental animal models have therefore become very important. Therefore, this study aimed to investigate the possible neuroprotective effect of D-cycloserine and L-serine against aluminum chloride (AlCl

Indexed as

aluminumAlzheimer’s diseaseD-cycloserineL-serineneuro-nutrientneuroprotective

Identifiers

PMID36159454
PMCPMC9493202

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.