Evidence map›Paper›PMID 36159291›Full record

ArticleFrontiers in public health2022

Association between blood lead levels and hyperlipidemiais: Results from the NHANES (1999-2018).

Yangchang Zhang, Weiwei Liu, Wei Zhang, Rui Cheng, Andi Tan, Shisi Shen, Yang Xiong, Limei Zhao, Xun Lei

Open access · goldAbstract read
In one paragraph

Article in Frontiers in public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 70 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 1 country.

Yangchang ZhangSchool of Public Health, Chongqing Medical University, Chongqing, China.
Weiwei LiuSchool of Public Health, Chongqing Medical University, Chongqing, China.
Wei ZhangChongqing College of Traditional Chinese Medicine, Chongqing, China.
Rui ChengJiangxi Provincial Key Laboratory of Preventive Medicine, School of Public Health, Nanchang University, Nanchang, China.
Andi TanInternational Business School, Yunnan University of Finance and Economics, Kunming, China.
Shisi ShenThe First School of Clinical Medicine, Chongqing Medical University, Chongqing, China.
Yang XiongWest China Hospital, Sichuan University, Chengdu, China.
Limei ZhaoChongqing Jiangjin Central Hospital, Chongqing, China.
Xun LeiSchool of Public Health, Chongqing Medical University, Chongqing, China.
Chongqing Medical University · CNChongqing Public Health Medical Center · CNFirst People's Hospital of Chongqing · CNJiangjin Central Hospital · CNNanchang University · CNWest China Hospital of Sichuan University · CNYunnan University of Finance And Economics · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Research on the association between blood lead (Pb) and lipid biomarkers have yielded inconsistent results, and epidemiological studies on blood Pb levels and hyperlipidemia are scarce. The present study aimed to examine the association between blood Pb levels and hyperlipidemia in adults from the National Health and Nutrition Examination Survey (NHANES). Methods: A total of 43,196 participants in the NHANES from 1999 to 2018 were included in the final analysis. Hyperlipidemia was determined based on the National Cholesterol Education Program guidelines. Blood Pb levels were assessed using inductively-coupled plasma mass spectrometry. Weighted multivariable logistic regression analysis and subgroup analysis were conducted to determine the correlation between blood Pb levels and hyperlipidemia. Results: In the multivariable logistic regression model, high blood Pb levels were significantly associated with hyperlipidemia after adjusting for confounders (OR 1.41; 95%CI: 1.18-1.67). Furthermore, elevated blood Pb levels were associated with an increased risk of hyperlipidemia across the four quartile (Q) groups (Q1: OR 1.00; Q2: OR 1.16 [95%CI: 1.04-1.29]; Q3: OR 1.39 [95%CI: 1.21-1.59]; and Q4: OR 1.33 [95%CI: 1.15-1.54]; Conclusion: The current study showed a positive association between blood lead levels and hyperlipidemia.

Indexed as

CholesterolLeadAdultBiomarkersElectrolytesFemaleHumansNutrition SurveysPregnancyBiomarkersCholesterolElectrolytesLeadadultsbloodenvironment pollutionhyperlipidemialeadNHANES

Identifiers

PMID36159291
PMCPMC9500574
OpenAlexW4295207018

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.