Evidence map›Paper›PMID 36159087›Full record

ArticleInternational journal of endocrinology2022

Impact of Visit-to-Visit Triglyceride-Glucose Index Variability on the Risk of Cardiovascular Disease in the Elderly.

Fei Chen, Ying Pan, Ziqing Liu, Rong Huang, Jing Wang, Jian Shao, Yaqin Gong, Xiyi Sun, Xiaobo Jiang, Weihao Wang and 4 more

Abstract read
In one paragraph

Article in International journal of endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
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  3. Observational
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  9. Outdoor walking, genetic predisposition, and the risk of incident osteoporosis among older adults: A prospective large population-based cohort study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Fei ChenCollege of Life Sciences, University of Chinese Academy of Sciences, China.ORCID https://orcid.org/0000-0002-1244-2194
Ying PanDepartment of Endocrinology, Kunshan Hospital Affiliated to Jiangsu University, Kunshan, Jiangsu, China.ORCID https://orcid.org/0000-0001-9935-6194
Ziqing LiuCollege of Life Sciences, University of Chinese Academy of Sciences, China.ORCID https://orcid.org/0000-0001-5907-0482
Rong HuangGuangzhou Laboratory, Guangzhou, Guangdong, China.ORCID https://orcid.org/0000-0002-9484-6802
Jing WangCollege of Life Sciences, University of Chinese Academy of Sciences, China.ORCID https://orcid.org/0000-0002-9272-5628
Jian ShaoCollege of Life Sciences, University of Chinese Academy of Sciences, China.ORCID https://orcid.org/0000-0001-7828-3459
Yaqin GongDepartment of Medical Informatics, Kunshan Hospital Affiliated to Jiangsu University, Kunshan, Jiangsu, China.ORCID https://orcid.org/0000-0001-8695-4048
Xiyi SunDepartment of Medical Informatics, Kunshan Hospital Affiliated to Jiangsu University, Kunshan, Jiangsu, China.ORCID https://orcid.org/0000-0001-9262-0554
Xiaobo JiangZhenChuan Community Health Service Center, Kunshan, Jiangsu, China.ORCID https://orcid.org/0000-0003-4165-4687
Weihao WangDepartment of Endocrinology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, China.ORCID https://orcid.org/0000-0002-5896-2793
Zhaoqiang LiGuangzhou Laboratory, Guangzhou, Guangdong, China.ORCID https://orcid.org/0000-0002-5151-6109
Shao ZhongDepartment of Endocrinology, Kunshan Hospital Affiliated to Jiangsu University, Kunshan, Jiangsu, China.ORCID https://orcid.org/0000-0002-9054-6554
Qi PanDepartment of Endocrinology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, China.ORCID https://orcid.org/0000-0002-2567-1439
Kaixin ZhouCollege of Life Sciences, University of Chinese Academy of Sciences, China.ORCID https://orcid.org/0000-0002-4751-7248

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The aging population is increasingly susceptible to cardiovascular disease (CVD). Visit-to-visit variability in glucose and lipid levels both contributed to CVD risk independent of their mean values. However, whether variability in the triglyceride-glucose (TyG) index is a risk factor for CVD remains unknown. Results: Over a median follow-up of 6.2 years, there were 2,178 CVD events. When participants were divided into four quartiles according to their TyG variability, after adjusting for established CVD risk factors, subjects in the top quartile had (HR = 1.18, 95% CI 1.05-1.34, Conclusions: High variability in TyG was significantly associated with elevated CVD risk in the elderly, independent of average TyG and other risk factors. Close monitoring variability in TyG might be informative to identify old individuals at high risk of CVD.

Identifiers

PMID36159087
PMCPMC9507760

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.