Evidence map›Paper›PMID 36159019›Full record

ArticleWorld journal of gastroenterology2022

Prevalence and clinical characteristics of autoimmune liver disease in hospitalized patients with cirrhosis and acute decompensation in China.

Zi-Xuan Shen, Dan-Dan Wu, Jie Xia, Xian-Bo Wang, Xin Zheng, Yan Huang, Bei-Ling Li, Zhong-Ji Meng, Yan-Hang Gao, Zhi-Ping Qian and 29 more

Abstract readMulticenter Study
In one paragraph

Article in World journal of gastroenterology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. [Analysis of the clinical characteristics of 45 cases of autoimmune liver disease in the Xizang population].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

39 authors.

Zi-Xuan ShenDepartment of Gastroenterology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China.
Dan-Dan WuDepartment of Gastroenterology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China.
Jie XiaDepartment of Infectious Diseases, Southwest Hospital, The Third Military Medical University (Army Medical University), Chongqing 400038, China.
Xian-Bo WangCenter of Integrative Medicine, Beijing Ditan Hospital, Capital Medical University, Beijing 100102, China.
Xin ZhengDepartment of Infectious Diseases, Institute of Infection and Immunology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, Hubei Province, China.
Yan HuangDepartment of Infectious Diseases, Hunan Key Laboratory of Viral Hepatitis, Xiangya Hospital, Central South University, Changsha 410008, Hunan Province, China.
Bei-Ling LiHepatology Unit, Department of Infectious Diseases, Nanfang Hospital, Southern Medical University, Guangzhou 510515, Guangdong Province, China.
Zhong-Ji MengDepartment of Infectious Disease, Taihe Hospital, Hubei University of Medicine, Shiyan 430418, Hubei Province, China.
Yan-Hang GaoDepartment of Hepatology, The First Hospital of Jilin University, Changchun 130031, Jilin Province, China.
Zhi-Ping QianDepartment of Liver Intensive Care Unit, Shanghai Public Health Clinical Centre, Fudan University, Shanghai 201508, China.
Feng LiuTianjin Institute of Hepatology, Nankai University Second People's Hospital, Tianjin 300102, China.
Xiao-Bo LuInfectious Disease Center, The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, Xinjiang, China.
Jia ShangDepartment of Infectious Diseases, Henan Provincial People's Hospital, Zhengzhou 450003, Henan Province, China.
Hua-Dong YanDepartment of Infectious Diseases, Hwamei Hospital, The Second Hospital of Ningbo, University of Chinese Academy of Sciences, Ningbo 315153, Zhejiang Province, China.
Yu-Bao ZhengDepartment of Infectious Diseases, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630, Guangdong Province, China.
Wen-Yi GuDepartment of Gastroenterology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China.
Yan ZhangDepartment of Gastroenterology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China.
Jian-Yi WeiDepartment of Gastroenterology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China.
Wen-Ting TanDepartment of Infectious Diseases, Southwest Hospital, The Third Military Medical University (Army Medical University), Chongqing 400038, China.
Yi-Xin HouCenter of Integrative Medicine, Beijing Ditan Hospital, Capital Medical University, Beijing 100102, China.
Qun ZhangCenter of Integrative Medicine, Beijing Ditan Hospital, Capital Medical University, Beijing 100102, China.
Yan XiongDepartment of Infectious Diseases, Institute of Infection and Immunology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, Hubei Province, China.
Cong-Cong ZouDepartment of Infectious Diseases, Institute of Infection and Immunology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, Hubei Province, China.
Jun ChenDepartment of Infectious Diseases, Hunan Key Laboratory of Viral Hepatitis, Xiangya Hospital, Central South University, Changsha 410008, Hunan Province, China.
Ze-Bing HuangDepartment of Infectious Diseases, Hunan Key Laboratory of Viral Hepatitis, Xiangya Hospital, Central South University, Changsha 410008, Hunan Province, China.
Xiu-Hua JiangHepatology Unit, Department of Infectious Diseases, Nanfang Hospital, Southern Medical University, Guangzhou 510515, Guangdong Province, China.
Sen LuoDepartment of Infectious Disease, Taihe Hospital, Hubei University of Medicine, Shiyan 430418, Hubei Province, China.
Yuan-Yuan ChenDepartment of Infectious Disease, Taihe Hospital, Hubei University of Medicine, Shiyan 430418, Hubei Province, China.
Na GaoDepartment of Hepatology, The First Hospital of Jilin University, Changchun 130031, Jilin Province, China.
Chun-Yan LiuDepartment of Hepatology, The First Hospital of Jilin University, Changchun 130031, Jilin Province, China.
Wei YuanDepartment of Liver Intensive Care Unit, Shanghai Public Health Clinical Centre, Fudan University, Shanghai 201508, China.
Xue MeiDepartment of Liver Intensive Care Unit, Shanghai Public Health Clinical Centre, Fudan University, Shanghai 201508, China.
Jing LiDepartment of Infectious Diseases and Hepatology, The Second Hospital of Shandong University, Jinan 250033, Shandong Province, China.
Tao LiDepartment of Infectious Diseases and Hepatology, The Second Hospital of Shandong University, Jinan 250033, Shandong Province, China.
Xin-Yi ZhouInfectious Disease Center, The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, Xinjiang, China.
Guo-Hong DengDepartment of Infectious Diseases, Southwest Hospital, The Third Military Medical University (Army Medical University), Chongqing 400038, China.
Jin-Jun ChenHepatology Unit, Department of Infectious Diseases, Nanfang Hospital, Southern Medical University, Guangzhou 510515, Guangdong Province, China.
Xiong MaDepartment of Gastroenterology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China.
Hai LiDepartment of Gastroenterology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAutoimmune liver disease (AILD) has been considered a relatively uncommon disease in China, epidemiological data for AILD in patients with cirrhosis and acute decompensation (AD) is sparse.

aimTo investigate the prevalence, outcome and risk factors for AILD in cirrhotic patients complicated with AD in China.

methodsWe collected data from patients with cirrhosis and AD from two prospective, multicenter cohorts in hepatitis B virus endemic areas. Patients were regularly followed up at the end of 28-d, 90-d and 365-d, or until death or liver transplantation (LT). The primary outcome in this study was 90-d LT-free mortality. Acute-on-chronic liver failure (ACLF) was assessed on admission and during 28-d hospitalization, according to the diagnostic criteria of the European Association for the Study of the Liver (EASL). Risk factors for death were analyzed with logistic regression model.

resultsIn patients with cirrhosis and AD, the overall prevalence of AILD was 9.3% (242/2597). Prevalence of ACLF was significantly lower in AILD cases (14%) than those with all etiology groups with cirrhosis and AD (22.8%) (

conclusionAILD was not rare in hospitalized patients with cirrhosis and AD in China, among which PBC was the most common etiology. 90-d LT-free mortality were independently associated with TB, HE and BUN.

Indexed as

Acute-On-Chronic Liver FailureHepatic EncephalopathyHepatitis, AutoimmuneLiver Cirrhosis, BiliaryBilirubinHumansLiver CirrhosisPrevalenceProspective StudiesBilirubinAcute-on-chronic liver failureAutoimmune liver diseaseCirrhosis and acute decompensationMortalityPrevalence

Identifiers

PMID36159019
PMCPMC9453760

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.