ArticleFrontiers in cardiovascular medicine2022
Hyperglycemia may increase deep vein thrombosis in trauma patients with lower limb fracture.
Article in Frontiers in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Machine Learning Model Predicts New-Onset Lower Extremity Deep Vein Thrombosis After Pelvic Fracture Surgery and Targeted Diagnosis.Clinical epidemiology · 2026Article
- Association between serum albumin levels and risk of deep vein thrombosis in diabetic patients: a retrospective case-control study.Hormones (Athens, Greece) · 2025Article
- Metabolic pathways in deep vein thrombosis: a new frontier for therapeutic intervention.Blood · 2025Review
- Risk Factors and Clinical Value of Deep Venous Thrombosis After Traumatic Lower Limb Fractures.Journal of clinical laboratory analysis · 2025Article
- Perioperative Hyperglycemia is an Independent Risk Factor for Venous Thromboembolism Events After Operative Treatment of Geriatric Femur Fractures.Geriatric orthopaedic surgery & rehabilitation · 2025Article
- Non-demographic dependent mechanisms of DVT formation in patients with traumatic limb fractures: an exploratory cohort study based on limited variable matching.American journal of translational research · 2025Article
- Is the coexistence of diabetes and hypertension liable for a higher risk of cardiovascular disorders among Saudis?American journal of blood research · 2025Article
- Metabolomic profiling of deep vein thrombosis.Phlebology · 2024Review
- High systemic inflammation response index level is associated with an increased risk of lower extremity deep venous thrombosis: a large retrospective study.Annals of medicine · 2023Article
- Association between systemic immune-inflammation index and risk of lower extremity deep venous thrombosis in hospitalized patients: a 10-year retrospective analysis.Frontiers in cardiovascular medicine · 2023Article
- Application of Novel Thrombosis Scale in Fracture Related Lower Extremity Deep Venous Thrombosis.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/HemostasisArticle
- Risk Factors of Deep Vein Thrombosis in Adults with Acute Compartment Syndrome Following Lower Extremity Fractures.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/HemostasisArticle
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8 authors.
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Abstract
Diabetes mellitus is associated with prothrombotic states and thrombotic events. This study examined the association between preoperative glucose levels and deep vein thrombosis (DVT) in trauma patients undergoing surgery for lower limb fracture. Data from 1,591 patients who underwent fracture surgery between January 2017 and March 2022 at the Affiliated Hospital of Qingdao University were queried from institutional electronic medical records. A total study population of 1,086 patients was identified, comprising 138 patients who experienced DVT and 948 controls. The primary outcome was DVT. Multiple logistic regression analyses were performed and a receiver operating characteristic (ROC) curve was generated. Age, D-dimer level, preoperative RBC count, and preoperative glucose level were independent predictors of DVT. The two highest categories of D-dimer level (≥ 960, < 2,102; ≥ 2,102 ng/ml) increased the odds ratio for DVT by 4.215 times [95% confidence interval (CI) 1.820-9.761] and 7.896 times (95% CI 3.449-18.074), respectively, compared with the lowest reference category (< 490 ng/ml). The area under the curve (AUC) for the preoperative glucose level was 0.605. Hyperglycemia (glucose ≥ 6.1, < 7.0 mmol/l) increased the odds of DVT by 1.889-fold [95% CI (1.085-3.291);
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