Evidence map›Paper›PMID 36158714›Full record

ArticleSleep science (Sao Paulo, Brazil)

Association of sleep-wake rhythm and sleep quality with endothelial function in young adults.

Honoka Nakashima, Akiko Noda, Anna Tamura, Michiaki Nagai, Masato Okuda, Takahiro Okumura, Fumihiko Yasuma, Toyoaki Murohara

Abstract read
In one paragraph

Article in Sleep science (Sao Paulo, Brazil). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Fluctuations in Sleep Duration and Timing and Cardiometabolic Risk.Arteriosclerosis, thrombosis, and vascular biology · 2026
    Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Do not sleep on vitamin D: vitamin D is associated with sleep variability in apparently healthy adults.American journal of physiology. Regulatory, integrative and comparative physiology · 2025
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Honoka NakashimaChubu University Graduate School of Life and Health Sciences, Department of Biomedical Sciences - Kasugai - Aichi - Japan.
Akiko NodaChubu University Graduate School of Life and Health Sciences, Department of Biomedical Sciences - Kasugai - Aichi - Japan.
Anna TamuraChubu University Collage of Life and Health Sciences, Department of Biomedical Sciences - Kasugai - Aichi - Japan.
Michiaki NagaiHiroshima City Asa Hospital, Hiroshima, Department of Cardiology - Hiroshima - Japan.
Masato OkudaChubu University Graduate School of Life and Health Sciences, Department of Biomedical Sciences - Kasugai - Aichi - Japan.
Takahiro OkumuraNagoya University Graduate School of Medicine, Department of Cardiology - Nagoya - Aichi - Japan.
Fumihiko YasumaChubu University Collage of Life and Health Sciences, Department of Biomedical Sciences - Kasugai - Aichi - Japan.
Toyoaki MuroharaNagoya University Graduate School of Medicine, Department of Cardiology - Nagoya - Aichi - Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The environment in modern society could disturb the sleep-wake rhythm. We aimed to study the association of sleep-wake rhythm with endothelial function and sleep quality. Material and Methods: Thirty-one healthy university students (mean age: 20.4±1.8 years) were enrolled. The endothelial function was evaluated with the percent endothelium-dependent flow-mediated dilation of the brachial artery [%FMD: (maximum diameter - baseline diameter)/baseline diameter x 100] using the high-resolution ultrasonography. We also measured the total sleep time (TST), sleep effciency, and the standard deviation (SD) of sleep timing (midpoint between bedtime and wake-up time) using the actigraphy. The irregular sleep-wake rhythm was defined as having the shift of bedtime or wake-up time for two hours or longer. Results: The %FMD and sleep efficiency were significantly lower in the irregular group than regular group (%FMD: 6.1±2.4 vs. 10.9±2.3, Conclusion: Our findings suggest that the irregular sleep-wake rhythm and poor sleep quality could have adverse effects on endothelial function in young adults.

Indexed as

ActigraphyCircadian RhythmYoung Adult

Identifiers

PMID36158714
PMCPMC9496482

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.