SynthesisFrontiers in aging neuroscience2022
Risk of dementia or cognitive impairment in COPD patients: A meta-analysis of cohort studies.
Synthesis in Frontiers in aging neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Impact of exercise training on cognitive function in patients with COPD: a systematic review and meta-analysis of randomised controlled trials.European respiratory review : an official journal of the European Respiratory Society · 2025Pooled it
- Pooled it
- Chronic obstructive pulmonary disease as a risk factor for cognitive impairment: a systematic review and meta-analysis.BMJ open respiratory research · 2024Pooled it
- Multidimensional cortical morphological alterations in COPD using explainable machine learning.iScience · 2026Article
- Alzheimer's disease and related dementias and related health conditions among American Indian and Alaska Native Medicare beneficiaries.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Association of soluble tumor necrosis factor receptor 1 with tau pathology, brain atrophy, and cognitive decline: a longitudinal study.BMC medicine · 2026Article
- Bloodwork-free Early Screening for Alzheimer's Disease via Comorbid Pattern Recognition in Electronic Health Records.Research square · 2026Article
- Sulcal depth-based individualized structural covariance networks reveal multi-level brain reorganization associated with cognitive performance in COPD.Frontiers in neuroscience · 2026Article
- Exploring COPD Participants' Experiences in a Comprehensive Telewellness Program within a Mixed-Disability Cohort: A Qualitative Study.International journal of chronic obstructive pulmonary disease · 2026Article
- Left precuneus ALFF is associated with arterial oxygenation and cognitive impairment in patients with COPD: a resting-state fMRI study.Frontiers in neurology · 2026Article
- Global Trends of Cognition-Targeted Interventions in Chronic Lung Disease: A Bibliometric and Visualized Analysis.International journal of chronic obstructive pulmonary disease · 2026Review
- Cigarette smoke-induced lung-brain barrier dysfunction drives neurocognitive impairment via inflammatory spill-over.Journal of neuroinflammation · 2025Article
- Timing of neurorehabilitation and subsequent Alzheimer's disease risk in patients with moderate to severe traumatic brain injury: A nationwide retrospective cohort study in the United States.Journal of Alzheimer's disease : JAD · 2025Article
- Cognitive decline before and after incident chronic respiratory disease.GeroScience · 2025Article
- Subjective Cognitive Decline in COPD - A Cross-Sectional Analysis of the Behavioral Risk Factor Surveillance System.Journal of general internal medicine · 2025Article
- Biological sex and age-associated changes in muscle and brain health in Chronic Obstructive Pulmonary Disease: A large cross-sectional study.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2025Article
- Mechanisms of cognitive impairment in arterial hypertension.World journal of psychiatry · 2025Article
- Identifying progression subphenotypes of Alzheimer's disease from large-scale electronic health records with machine learning.Journal of biomedical informatics · 2025Article
- Construction and evaluation of nomogram for risk prediction of cognitive impairment in chronic obstructive pulmonary disease comorbidity.BMC psychology · 2025Article
- Sex differences in clinical risk factors for Alzheimer's dementia patients with early-onset and late-onset.Frontiers in global women's health · 2025Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: A meta-analysis of cohort studies was performed to evaluate the association between COPD and the risk of dementia or cognitive impairment. Methods: Cohort studies that evaluated the association between COPD and the risk of dementia or cognitive impairment were identified by a systematic search of PubMed, Embase, Web of Science, and Cochrane Library databases. The search time frame was from database establishment to April 12, 2022, with two reviewers independently screening the literature and extracting data. The Newcastle-Ottawa Quality Assessment Scale (NOS) was used to conduct the quality evaluation. Then, a meta-analysis was performed using Stata 15.1 software. Results: Six cohort studies including 428,030 participants were included. The overall quality of the included studies was high, with an average NOS score of over 7. Meta-analysis showed that compared to those without COPD at baseline, patients with COPD were associated with a significant increased risk of dementia ( Conclusion: COPD patients have a higher risk of developing dementia or cognitive impairment compared to those without COPD, and this risk is not affected by gender but seems to be associated with age. Systematic review registration: https://www.crd.york.ac.uk/prospero/, identifier CRD42022325832.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.