Evidence map›Paper›PMID 36158413›Full record

ArticleCureus2022

The Great Mimicker: Cutaneous Metastatic Melanoma Presenting as a Non-resolving Pleural Effusion.

Jackeline P Vajta Gomez, Om Parkash, Rebecca Joseph, Janani Arangan, Winston Magno, Monzurul Chowdhury, Carolina Borz-Baba, Consuelito Medrano

Abstract readCase Reports
In one paragraph

Article in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jackeline P Vajta GomezInternal Medicine, St. Mary's Hospital, Waterbury, USA.
Om ParkashInternal Medicine, Icahn School of Medicine, Mount Sinai Hospital, New York, USA.
Rebecca JosephInternal Medicine, St. Mary's Hospital, Waterbury, USA.
Janani AranganInternal Medicine, St. Mary's Hospital, Waterbury, USA.
Winston MagnoPathology, St. Mary's Hospital, Waterbury, USA.
Monzurul ChowdhuryNephrology, St. Mary's Hospital, Waterbury, USA.
Carolina Borz-BabaInternal Medicine, St. Mary's Hospital, Waterbury, USA.
Consuelito MedranoHematology and Oncology, St. Mary's Hospital, Waterbury, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although melanoma starts as a local disease, it can metastasize to other sites of the body including the lung, brain, liver, and intestines. However, pleural involvement is a rare presentation. Here, we present a case of a 57-year-old man with a history of stage IIA cutaneous melanoma, that relapsed 3 years after cutaneous resection, presenting with a non-resolving pleural effusion. Pleural fluid analysis was consistent with an exudative effusion, and pleural biopsy confirmed metastatic melanoma. The patient was treated with dual therapy of ipilimumab and nivolumab, as per National Comprehensive Cancer Network guidelines, with good response. Thus, we recommend having a high index of clinical suspicion for metastatic pleural melanoma when a patient with a history of cutaneous melanoma presents with a non-resolving pleural effusion.

Indexed as

cancer immunotherapycutaneous melanomamalignantmetastaticnon-resolving pleural effusion

Identifiers

PMID36158413
PMCPMC9499834

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.