Evidence map›Paper›PMID 36158332›Full record

ArticleCureus2022

Psychostimulants for the Treatment of Comorbid Post-traumatic Stress Disorder (PTSD) in a Patient With Attention-Deficit/Hyperactivity Disorder (ADHD): A Case Report and Literature Summary.

Claudette Barreto, Ana Vila Irigoyen, Olga Lopez, Leonard Gralnik

Registry-linked trialAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07664631 (Effects of Stimulant Medications in PTSD), which is not on this map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07664631 phase1not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Effects of Stimulant Medications in PTSD

TypeinterventionalSponsorUniversity of ChicagoRan2026 to 2027Enrolled40ConditionsAdderall, PTSD, Post Traumatic Stress DisorderArmsPlacebo, Adderall
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Claudette BarretoMedicine, Florida International University, Herbert Wertheim College of Medicine, Miami, USA.
Ana Vila IrigoyenMedicine, Florida International University, Herbert Wertheim College of Medicine, Miami, USA.
Olga LopezMedicine, Florida International University, Herbert Wertheim College of Medicine, Miami, USA.
Leonard GralnikPsychiatry, Florida International University, Herbert Wertheim College of Medicine, Miami, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present a case of a 35-year-old female with an extensive history of attention-deficit/hyperactivity disorder (ADHD) who experienced a traumatic sexual and physical assault and later developed post-traumatic stress disorder (PTSD). The patient disclosed that her current medication (Vyvanse) used to treat ADHD has been the only treatment modality that has helped control her intrusive thoughts and nightmares. Decreased dopaminergic receptors are associated with developing PTSD and psychostimulants are known to have an effect of increasing Dopamine release. This case report shows promising results and potential off-label use of psychostimulants for the treatment of PTSD.

Indexed as

attention-deficit/hyperactivity disorder (adhd)intrusive thoughtspost-traumatic stress disorder (ptsd)psychostimulantsschedule ii stimulantsstimulants use

Identifiers

PMID36158332
PMCPMC9484295

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.