ArticleWorld journal of gastrointestinal surgery2022
Impact of comorbid renal dysfunction in patients with hepatocellular carcinoma on long-term outcomes after curative resection.
Article in World journal of gastrointestinal surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed.
- Low preoperative serum creatinine levels are associated with poor prognosis in patients with hepatocellular carcinoma after liver resection: a multicenter study.BMC gastroenterology · 2025Article
- Tips for Preparing and Practicing Thermal Ablation Therapy of Hepatocellular Carcinoma.Cancers · 2023Review
- Perspectives on the Underlying Etiology of HCC and Its Effects on Treatment Outcomes.Journal of hepatocellular carcinoma · 2023Review
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11 authors.
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Abstract
backgroundHepatocellular carcinoma (HCC) is one of the most common malignancies worldwide. However, the number of patients with chronic kidney disease (CKD) is on the rise because of the increase in lifestyle-related diseases.
aimTo establish a tailored management strategy for HCC patients, we evaluated the impact of comorbid renal dysfunction (RD), as stratified by using the estimated glomerular filtration rate (EGFR), and assessed the oncologic validity of hepatectomy for HCC patients with RD.
methodsWe enrolled 800 HCC patients who underwent hepatectomy between 1997 and 2015 at our university hospital. We categorized patients into two (RD, EGFR < 60 mL/min/1.73 m
resultsThe RD patients were significantly older and had lower serum total bilirubin, aspartate aminotransferase, and aspartate aminotransferase levels than the non-RD patients (
conclusionComorbid mild RD had a negligible impact on the prognosis of HCC patients who underwent curative hepatectomy with appropriate perioperative management, and close attention to severe CKD is necessary to prevent postoperative bleeding and surgical site infection.
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