Evidence map›Paper›PMID 36158166›Full record

ArticleCardiogenetics2021

Human

Shreyas A Bhave, Dong-Chuan Guo, Stoyan Angelov, Michael J Bamshad, Deborah A Nickerson, Dianna Milewicz, Mary C Wallingford

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cardiogenetics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Shreyas A BhaveMolecular Cardiology Research Institute, Tufts Medical Center, Boston, MA, US.
Dong-Chuan GuoDepartment of Internal Medicine, McGovern Medical School, University of Texas Health Science Center at Houston (UTHealth), Houston, Texas, US.
Stoyan AngelovDivision of Cardiology, University of Washington School of Medicine, Seattle, WA, US.
Michael J BamshadGenome Sciences, University of Washington, Seattle, Washington, US.
Deborah A NickersonGenome Sciences, University of Washington, Seattle, Washington, US.
Dianna MilewiczDepartment of Internal Medicine, McGovern Medical School, University of Texas Health Science Center at Houston (UTHealth), Houston, Texas, US.
Mary C WallingfordMolecular Cardiology Research Institute, Tufts Medical Center, Boston, MA, US.
University of Washington · USThe University of Texas Health Science Center at Houston · USTufts Medical Center · US

Funding

UW Center for Mendelian GenomicsUM1HG006493 · NHGRI · UNIVERSITY OF WASHINGTON · PI BAMSHAD, MICHAEL JOSEPH, LEAL, SUZANNE M · 2016 to 2020
$15.3M
Genetic Predisposition To Thoracic Aortic Aneurysms/DissectionsR01HL109942 · NHLBI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MILEWICZ, DIANNA M · 2012 to 2023
$7.5M
NHGRI Genome Sequencing Program Coordinating CenterU24HG008956 · NHGRI · RUTGERS, THE STATE UNIV OF N.J. · PI BUYSKE, STEVEN G, MATISE, TARA C. · 2016 to 2020
$4.9M
Determination of maternal-fetal phosphate transport mechanisms and the role of sodium-dependent phosphate transporters in extraembryonic tissuesR00HD090198 · NICHD · TUFTS MEDICAL CENTER · PI WALLINGFORD, MARY CATHERINE · 2018 to 2020
$747k
HiSeq X SequencerS10OD021553 · OD · UNIVERSITY OF WASHINGTON · PI NICKERSON, DEBORAH A · 2016 to 2016
$600k
NHGRI NIH HHS U24 HG008956NHGRI NIH HHS UM1 HG006493NHLBI NIH HHS R01 HL109942NICHD NIH HHS R00 HD090198NIH HHS S10 OD021553
6 · The paper itself

Abstract

Thoracic aortic aneurysms (TAAs) that progress to acute thoracic aortic dissections (TADs) are life threatening vascular events that have been associated with altered transforming growth factor (TGF) β signaling. In addition to TAA, multiple genetic vascular disorders, including hereditary hemorrhagic telangiectasia (HHT), involve altered TGFβ signaling and vascular malformations. Due to the importance of TGFβ, genomic variant databases have been curated for activin receptor-like kinase 1 (

Indexed as

genomic variantshereditary hemorrhagic telangiectasiaSMAD4thoracic aortic aneurysmvascular malformations

Identifiers

PMID36158166
PMCPMC9495981
OpenAlexW3195898211

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.