SynthesisComputational and mathematical methods in medicine2022
The Association of Sperm DNA Fragment and Assisted Reproductive Outcomes: A Meta-Analysis.
Synthesis in Computational and mathematical methods in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Impact of short abstinence versus testicular sperm on sperm DNA fragmentation: a systematic review and meta-analysis.Archives of gynecology and obstetrics · 2024Pooled it
- Sperm DNA Fragmentation in Native Semen: A Reflection of Apoptotic and Non-Viable Spermatozoa and Its Implications for Assisted Reproduction.International journal of molecular sciences · 2026Article
- Redox-Genomic Crosstalk: Linking Oxidative Stress, Sperm DNA Fragmentation, and Epigenetics in Personalized Management of Male Infertility.Journal of personalized medicine · 2026Review
- Sperm DNA fragmentation and assisted reproduction: an umbrella meta-analysis.European journal of medical research · 2026Article
- Sperm Selection Procedures in Cases of High Sperm DNA Fragmentation Index.Advances in experimental medicine and biology · 2026Review
- Comparing Methods for Sperm DNA Fragmentation Detection.Advances in experimental medicine and biology · 2026Review
- Sperm DNA fragmentation index did not associate with assisted reproductive outcomes: a cohort retrospective study of 5784 IVF/ICSI cycles.Journal of assisted reproduction and genetics · 2025Article
- Comparison of Embryological Results of Microinjection in Two Groups of Men with and without Requesting Sperm DNA Fragmentation Index Measurement.BioMed research international · 2024Article
- Sperm DNA fragmentation testing in clinical management of reproductive medicine.Reproductive medicine and biologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: To analyze the effect of sperm DNA fragmentation index (DFI) on the outcomes of in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI). Methods: Literature search was conducted on English databases PubMed, Cochrane, and Embase to obtain eligible studies. Results: A total of 11 cohort studies were included and analyzed using the random effects model. The results illustrated that the IVF fertilization rate (RR = 0.94, 95% CI: 0.77-1.14, Conclusion: This study has observed no significant correlation between sperm DFI and assisted reproductive outcomes. Multicenter large-sample clinical trials are required to conclusively determine the impact of DNA damage on the clinical outcomes of assisted reproduction.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.