Evidence map›Paper›PMID 36157988›Full record

Trial reportWorld journal of clinical cases2022

Dexmededomidine in pediatric unilateral internal inguinal ring ligation.

Guang Liu, Ling Zhang, Hui-Se Wang, Yi Lin, Hong-Quan Jin, Xiao-Dan Wang, Wei-Na Qiao, Ya-Tao Zhang, Jiao-Qian Sun, Zhi-Na Liu

Abstract readClinical Trial
In one paragraph

Trial report in World journal of clinical cases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Guang LiuDepartment of Anesthesiology, Baoding Children's Hospital, Baoding 071000, Hebei Province, China.
Ling ZhangDepartment of Anesthesiology, Baoding Children's Hospital, Baoding 071000, Hebei Province, China.
Hui-Se WangDepartment of Anesthesiology, Baoding Children's Hospital, Baoding 071000, Hebei Province, China.
Yi LinDepartment of Anesthesiology, Baoding Children's Hospital, Baoding 071000, Hebei Province, China.
Hong-Quan JinDepartment of Anesthesiology, Baoding Children's Hospital, Baoding 071000, Hebei Province, China.
Xiao-Dan WangDepartment of Anesthesiology, Baoding Children's Hospital, Baoding 071000, Hebei Province, China.
Wei-Na QiaoDepartment of Anesthesiology, Baoding Children's Hospital, Baoding 071000, Hebei Province, China.
Ya-Tao ZhangDepartment of Anesthesiology, Baoding Children's Hospital, Baoding 071000, Hebei Province, China.
Jiao-Qian SunDepartment of Anesthesiology, Baoding Children's Hospital, Baoding 071000, Hebei Province, China.
Zhi-Na LiuDepartment of Anesthesiology, Baoding Children's Hospital, Baoding 071000, Hebei Province, China. wenwen9604@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSafe and effective analgesia strategy remains one of the priorities for pediatric inguinal hernia treatment.

aimTo explore safety and efficacy of dexmededomidine monotherapy for postoperative analgesia in children who received laparoscopic unilateral internal inguinal ring ligation.

methodsThis randomized single-center controlled trial included 390 children (aged 1-3 years, ASA grade I-II), randomly divided into a dexmededomidine group (D group), a dexmededomidine + sufentanil group (DS group), and a sufentanil group (S group). The primary endpoint was percentage of children with the Face, Legs, Activity, Cry, and Consolability (FLACC) score ≤ 3 points 2 h after surgery.

resultsThe comparisons of the FLACC scores at 2, 4, 6, 8, 12, and 24 h were not significantly different among the three groups (

conclusionAnalgesic effects of dexmededomidine monotherapy are comparable to those of sufentanil alone or in combination with dexmededomidine for children who underwent laparoscopic unilateral internal inguinal ring ligation, with better sedative effects and a lower incidence of adverse events.

Indexed as

AnalgesicsChildDexmededomidineInguinal herniaLaparoscopyPain management

Identifiers

PMID36157988
PMCPMC9353900

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.