ArticleMedicine in novel technology and devices2022
Computational fluid dynamics analysis and experimental hemolytic performance of three clinical centrifugal blood pumps: Revolution, Rotaflow and CentriMag.
Article in Medicine in novel technology and devices, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 41 citations in OpenAlex.
- Hematologic complications and design challenges in cardiovascular devices.Communications engineering · 2026Review
- Hemodynamic performance and blood damage of the Intra-aortic pumps: A CFD-Based investigation.Medical & biological engineering & computing · 2026Article
- Computational and Experimental Assessment of Shear-Induced Blood Trauma by HeartMate II, HeartMate 3, and BrioVAD.ASAIO journal (American Society for Artificial Internal Organs : 1992) · 2026Article
- Article
- A Biophysics-Based Mathematical Model of Shear-Induced Platelet Activation and Receptor Shedding: Re-Examining Previous Experimental Data.ASAIO journal (American Society for Artificial Internal Organs : 1992) · 2025Article
- Open-access smart blood pump platform for controlling extracorporeal membrane oxygenation.HardwareX · 2025Article
- Characteristics and hemolysis analysis of centrifugal blood pumps under different speed modulations.Frontiers in physiology · 2025Article
- Mechanically-foldable axial flow blood pump: response-surface-based structural optimization and hemolytic performance evaluation.Frontiers in physiology · 2025Article
- Analysis of fluid forces impacting on the impeller of a mixed flow blood pump with computational fluid dynamics.The International journal of artificial organs · 2024Article
- Analysis of non-physiological shear stress-induced red blood cell trauma across different clinical support conditions of the blood pump.Medical & biological engineering & computing · 2024Article
- In vitro study on device-induced damage to blood cellular components and degradation of von Willebrand factor in a CentriMag pump-assisted circulation.Artificial organs · 2024Article
- Design Optimization of a Phototherapy Extracorporeal Membrane Oxygenator for Treating Carbon Monoxide Poisoning.Bioengineering (Basel, Switzerland) · 2023Article
- Resistance valves in circulatory loops have a significant impact onFrontiers in physiology · 2023Article
- Role of thrombin to non-physiological shear stress induced platelet activation and function alternation.Thrombosis research · 2022Article
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
Centrifugal blood pumps have become popular for adult extracorporeal membrane oxygenation (ECMO) due to their superior blood handling and reduced thrombosis risk featured by their secondary flow paths that avoid stagnant areas. However, the high rotational speed within a centrifugal blood pump can introduce high shear stress, causing a significant shear-induced hemolysis rate. The Revolution pump, the Rotaflow pump, and the CentriMag pump are three of the leading centrifugal blood pumps on the market. Although many experimental and computational studies have focused on evaluating the hydraulic and hemolytic performances of the Rotaflow and CentriMag pumps, there are few on the Revolution pump. Furthermore, a thorough direct comparison of these three pumps' flow characteristics and hemolysis is not available. In this study, we conducted a computational and experimental analysis to compare the hemolytic performances of the Revolution, Rotaflow, and CentriMag pumps operating under a clinically relevant condition, i.e., the blood flow rate of 5 L/min and pump pressure head of 350 mmHg, for adult ECMO support.
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