Evidence map›Paper›PMID 36157742›Full record

ReviewACS omega2022

Inspirations of Biomimetic Affinity Ligands: A Review.

Aykut Arif Topçu, Seçkin Kılıç, Erdoğan Özgür, Deniz Türkmen, Adil Denizli

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in ACS omega, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. One-Step Purification of Recombinant Cutinase from anBiomimetics (Basel, Switzerland) · 2024
    Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Aykut Arif TopçuMedical Laboratory Program, Vocational School of Health Service, Aksaray University, 68100 Aksaray, Turkey.
Seçkin KılıçDepartment of Chemistry, Hacettepe University, 06230 Ankara, Turkey.
Erdoğan ÖzgürDepartment of Chemistry, Hacettepe University, 06230 Ankara, Turkey.
Deniz TürkmenDepartment of Chemistry, Hacettepe University, 06230 Ankara, Turkey.ORCID https://orcid.org/0000-0003-0161-172X
Adil DenizliDepartment of Chemistry, Hacettepe University, 06230 Ankara, Turkey.ORCID https://orcid.org/0000-0002-6916-3356

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Affinity chromatography is a well-known method dependent on molecular recognition and is used to purify biomolecules by mimicking the specific interactions between the biomolecules and their substrates. Enzyme substrates, cofactors, antigens, and inhibitors are generally utilized as bioligands in affinity chromatography. However, their cost, instability, and leakage problems are the main drawbacks of these bioligands. Biomimetic affinity ligands can recognize their target molecules with high selectivity. Their cost-effectiveness and chemical and biological stabilities make these antibody analogs favorable candidates for affinity chromatography applications. Biomimetics applies to nature and aims to develop nanodevices, processes, and nanomaterials. Today, biomimetics provides a design approach to the biomimetic affinity ligands with the aid of computational methods, rational design, and other approaches to meet the requirements of the bioligands and improve the downstream process. This review highlighted the recent trends in designing biomimetic affinity ligands and summarized their binding interactions with the target molecules with computational approaches.

Identifiers

PMID36157742
PMCPMC9494661

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.