Evidence map›Paper›PMID 36157658›Full record

ArticleWorld journal of clinical cases2022

Chlorine poisoning caused by improper mixing of household disinfectants during the COVID-19 pandemic: Case series.

Guo-Dong Lin, Jie-Yi Wu, Xiao-Bo Peng, Xiao-Xia Lu, Zhong-Ying Liu, Zhi-Guo Pan, Ze-Wu Qiu, Jian-Guang Dong

Abstract read
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Article in World journal of clinical cases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Guo-Dong LinDepartment of Critical Care Medicine, General Hospital of Southern Theater Command of PLA, Guangzhou 510010, Guangdong Province, China.
Jie-Yi WuDepartment of Critical Care Medicine, General Hospital of Southern Theater Command of PLA, Guangzhou 510010, Guangdong Province, China.
Xiao-Bo PengSenior Department of Hematology, The Fifth Medical Center of PLA General Hospital, Beijing 100071, China.
Xiao-Xia LuSenior Department of Hematology, The Fifth Medical Center of PLA General Hospital, Beijing 100071, China.
Zhong-Ying LiuSenior Department of Hematology, The Fifth Medical Center of PLA General Hospital, Beijing 100071, China.
Zhi-Guo PanDepartment of Critical Care Medicine, General Hospital of Southern Theater Command of PLA, Guangzhou 510010, Guangdong Province, China.
Ze-Wu QiuSenior Department of Hematology, The Fifth Medical Center of PLA General Hospital, Beijing 100071, China.
Jian-Guang DongSenior Department of Hematology, The Fifth Medical Center of PLA General Hospital, Beijing 100071, China. 347800520@qq.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMisuse of disinfectants during the coronavirus disease 2019 pandemic has led to several poisoning incidents. However, there are few clinical case reports on poisoning caused by improper mixing of household disinfectants.

aimTo summarize the clinical characteristics and treatment effects of chlorine poisoning caused by improper mixing of hypochlorite bleach with acidic cleaning agents. METHODSWe retrospectively analyzed baseline and clinical data, clinical symptoms, and treatment methods of seven patients with chlorine poisoning who were admitted to the National Army Poisoning Treatment Center.

resultsAmong the seven patients, the average poisoning time (exposure to admission) was 57 h (4-240 h). All patients were involved in cleaning bathrooms. Chest computed tomography scans revealed bilateral lung effusions or inflammatory changes in five patients. The partial pressure of oxygen decreased in six patients, and respiratory failure occurred in one. Five patients had different degrees of increase in white blood cell count. Humidified oxygen therapy, non-invasive mechanical ventilation, anti-inflammatory corticosteroids, antioxidants, and antibiotics were administered for treatment. The average length of hospital stay was 7 d (4-9 d). All seven patients recovered and were discharged.

conclusionImproper mixing of household disinfectants may cause damage to the respiratory system due to chlorine poisoning. Corticosteroids may improve lung exudation in severe cases, and symptomatic supportive treatment should be performed early.

Indexed as

Acidic cleaning agentsChlorine poisoningHousehold disinfectantHypochlorite bleachToxic lung injury

Identifiers

PMID36157658
PMCPMC9477020

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