Evidence map›Paper›PMID 36157630›Full record

ArticleNeurology. Clinical practice2022

COVID-19 Outcomes in Hospitalized Patients With Neurodegenerative Disease: A Retrospective Cohort Study.

Roshni Abee Patel, Glenn T Stebbins, Ekta B Kishen, Brandon Barton

Abstract read
In one paragraph

Article in Neurology. Clinical practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Roshni Abee PatelDepartment of Neurological Sciences (RAP, GTS, BB), Rush University Medical Center, Chicago, IL; Bioinformatics and Biostatistics Core (EBK), Rush University Medical Center, Chicago, IL; and Neurology Service (BB), Jesse Brown Veterans Affairs Medical Center, Chicago, IL.
Glenn T StebbinsDepartment of Neurological Sciences (RAP, GTS, BB), Rush University Medical Center, Chicago, IL; Bioinformatics and Biostatistics Core (EBK), Rush University Medical Center, Chicago, IL; and Neurology Service (BB), Jesse Brown Veterans Affairs Medical Center, Chicago, IL.
Ekta B KishenDepartment of Neurological Sciences (RAP, GTS, BB), Rush University Medical Center, Chicago, IL; Bioinformatics and Biostatistics Core (EBK), Rush University Medical Center, Chicago, IL; and Neurology Service (BB), Jesse Brown Veterans Affairs Medical Center, Chicago, IL.
Brandon BartonDepartment of Neurological Sciences (RAP, GTS, BB), Rush University Medical Center, Chicago, IL; Bioinformatics and Biostatistics Core (EBK), Rush University Medical Center, Chicago, IL; and Neurology Service (BB), Jesse Brown Veterans Affairs Medical Center, Chicago, IL.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Objectives: COVID-19 outcomes in patients with neurodegenerative disorders (NDs) are not well understood, and we hypothesize that there may be increased morbidity and mortality in this group. Methods: This was a retrospective cohort study performed at 3 hospitals in the Chicagoland area. All patients hospitalized with COVID-19 infection with ND during a 3-month period (March 15, 2020-June 15, 2020) were included and compared with age-matched controls (CL) at 1:1 ratio. Primary outcomes were death, intensive care unit (ICU) admission, and invasive ventilation. Secondary outcomes included presenting COVID-19 symptoms, development of encephalopathy, supplementary oxygen use, discharge disposition, and risk factors for mortality. Results: The study included 132 patients with neurodegenerative disorders and 132 age-matched CL. Ninety-day mortality (ND 19.7% vs CL 23.5%, Discussion: We found that there was no difference in short-term mortality of patients with ND hospitalized for COVID-19 compared with CL, but they may have higher rates of neurologic complications and disability. Future studies should address long-term outcomes.

Identifiers

PMID36157630
PMCPMC9491511

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.