Evidence map›Paper›PMID 36157547›Full record

ReviewWorld journal of gastroenterology2022

Clinical challenge for gastroenterologists-Gastrointestinal manifestations of systemic mastocytosis: A comprehensive review.

Alessandra Elvevi, Elena Maria Elli, Martina Lucà, Miki Scaravaglio, Fabio Pagni, Stefano Ceola, Laura Ratti, Pietro Invernizzi, Sara Massironi

Abstract readReview
In one paragraph

Review in World journal of gastroenterology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Role of Mast Cells in Eosinophilic Gastrointestinal Diseases.Immunology and allergy clinics of North America · 2024
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alessandra ElveviGastroenterology Division, San Gerardo Hospital, University of Milano - Bicocca School of Medicine, Monza 20900, Italy.
Elena Maria ElliHematology Division and Bone Marrow Transplant Unit, San Gerardo Hospital, Monza 20900, Italy.
Martina LucàGastroenterology Division, San Gerardo Hospital, University of Milano - Bicocca School of Medicine, Monza 20900, Italy.
Miki ScaravaglioGastroenterology Division, San Gerardo Hospital, University of Milano - Bicocca School of Medicine, Monza 20900, Italy.
Fabio PagniDepartment of Medicine and Surgery, Section of Pathology, San Gerardo Hospital, University of Milano - Bicocca School of Medicine, Monza 20900, Italy.
Stefano CeolaDepartment of Medicine and Surgery, Section of Pathology, San Gerardo Hospital, University of Milano - Bicocca School of Medicine, Monza 20900, Italy.
Laura RattiGastroenterology Division, San Gerardo Hospital, University of Milano - Bicocca School of Medicine, Monza 20900, Italy.
Pietro InvernizziGastroenterology Division, San Gerardo Hospital, University of Milano - Bicocca School of Medicine, Monza 20900, Italy.
Sara MassironiGastroenterology Division, San Gerardo Hospital, University of Milano - Bicocca School of Medicine, Monza 20900, Italy. sara.massironi@libero.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mastocytosis is a rare and heterogeneous disease characterized by various clinical and biological features that affect different prognoses and treatments. The disease is usually divided into 2 principal categories: cutaneous and systemic disease (SM). Clinical features can be related to mast cell (MC) mediator release or pathological MC infiltration. SM is a disease often hard to identify, and the diagnosis is based on clinical, biological, histological, and molecular criteria with different specialists involved in the patient's clinical work-up. Among all manifestations of the disease, gastrointestinal (GI) symptoms are common, being present in 14%-85% of patients, and can significantly impair the quality of life. Here we review the data regarding GI involvement in SM, in terms of clinical presentations, histological and endoscopic features, the pathogenesis of GI symptoms, and their treatment.

Indexed as

GastroenterologistsGastrointestinal DiseasesMastocytosisMastocytosis, SystemicHumansMast CellsQuality of LifeGastrointestinal involvementGastrointestinal symptomsSystemic mastocytosis

Identifiers

PMID36157547
PMCPMC9367223

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.