ArticleFrontiers in endocrinology2022
The role of endometrial thickness in predicting ectopic pregnancy after
Article in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Risk factors of ectopic pregnancy after in vitro fertilization-embryo transfer in Chinese population: A meta-analysis.PloS one · 2024Pooled it
- Development and validation of a nomogram for predicting ectopic pregnancy in patients receiving double fresh cleavage stage embryo transfer.Scientific reports · 2025Article
- Establishing a predictive model for ectopic pregnancy risk following assisted reproductive technology.BMC pregnancy and childbirth · 2025Article
- Determining the Factors Predicting the Success of Medical Management in Patients with Ectopic Pregnancy : Medical management in patients with ectopic pregnancy.Galen medical journal · 2025Article
- Clinical outcomes of frozen-thawed single blastocyst transfer derived from low-quality day 3 embryos: A retrospective cohort study.Frontiers in endocrinology · 2025Article
- Effects of chromosomal translocation characteristics on fertilization and blastocyst development - a retrospective cohort study.BMC medical genomics · 2023Article
- Establishment of a prediction model for the impact of endometrial thickness on the day of embryo transfer on ectopic pregnancy in frozen-thawed embryo transfer cycle.Frontiers in endocrinology · 2023Article
- Endometrial thickness and early pregnancy complications after frozen-thawed embryo transfers.Frontiers in endocrinology · 2023Article
- Clinical outcome analysis of frozen-thawed embryo transfer on Day 7.Frontiers in endocrinology · 2022Article
- Endometrial thickness as a predictive value of ectopic pregnancy in in-vitro fertilization/intracytoplasmic sperm injection cycles: a case-control study.Annals of Saudi medicineArticle
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10 authors.
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Abstract
Objective: To explore the risk factors of ectopic pregnancy after Methods: This retrospective cohort study was conducted at the Reproductive Medical Center of the Third Affiliated Hospital of Zhengzhou University from January 2016 to April 2020. Univariate and multivariate analysis were used to analyze the related factors affecting the occurrence of ectopic pregnancy (EP) and to construct a nomographic prediction model for the incidence of ectopic pregnancy. Results: A total of 12,766 cycles of 10109 patients were included, comprising 214 cases of EP and 12,552 cases of intrauterine pregnancy (IUP). Multivariate logistic regression analysis showed that the tubal factor was associated with a 2-fold increased risk for EP (aOR = 2.72, 95% CI: 1.69-4.39, P < 0.0001). A stratified analysis showed that women with an endometrial thickness (EMT) between 7.6 to 12.1mm (aOR = 0.57, 95%CI: 0.36-0.90, P = 0.0153) and >12.1mm (aOR = 0.42, 95%CI: 0.24-0.74, P = 0.0026) had a significant reduction of the risk of EP compared to women with an EMT of <7.6mm. Compared to cleavage stage transfer, blastocyst transfer can reduce the risk of ectopic pregnancy (aOR = 0.36, 95%CI: 0.26-0.50, P < 0.0001). The saturation model (full mode) establishes a nomographic prediction model with an AUC = 0.68 and a sensitivity and specificity of 0.67and 0.64, respectively. The nomination model was internally verified by self-sampling method (bootstrap sampling resampling times = 500). The resulting AUC = 0.68 (sensitivity: 0.65; specificity: 0.65) showed that the model was relatively stable. Conclusions: Our findings indicate that EMT is inversely proportional to the risk of EP. Embryo stage, number of embryos transferred were also significantly associated with EP rate. A simple nomogram for the predicting the risk of EP was established in order to reduce the occurrence of EP.
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