Evidence map›Paper›PMID 36157439›Full record

ArticleFrontiers in endocrinology2022

Trabecular bone score and phalangeal quantitative ultrasound are associated with muscle strength and fracture risk in hemodialysis patients.

Antonino Catalano, Agostino Gaudio, Federica Bellone, Mattia Miriam La Fauci, Anastasia Xourafa, Guido Gembillo, Giorgio Basile, Giuseppe Natale, Giovanni Squadrito, Francesco Corica and 2 more

Abstract read
In one paragraph

Article in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Antonino CatalanoDepartment of Clinical and Experimental Medicine, University Hospital of Messina, Messina, Italy.
Agostino GaudioDepartment of Clinical and Experimental Medicine, University Hospital of Catania, Catania, Italy.
Federica BelloneDepartment of Clinical and Experimental Medicine, University Hospital of Messina, Messina, Italy.
Mattia Miriam La FauciDepartment of Clinical and Experimental Medicine, University Hospital of Messina, Messina, Italy.
Anastasia XourafaDepartment of Clinical and Experimental Medicine, University Hospital of Catania, Catania, Italy.
Guido GembilloDepartment of Clinical and Experimental Medicine, University Hospital of Messina, Messina, Italy.
Giorgio BasileDepartment of Clinical and Experimental Medicine, University Hospital of Messina, Messina, Italy.
Giuseppe NataleMineral Metabolism and Nephrology Clinic of Vibo Valentia Hospital, Vibo Valentia, Italy.
Giovanni SquadritoDepartment of Clinical and Experimental Medicine, University Hospital of Messina, Messina, Italy.
Francesco CoricaDepartment of Clinical and Experimental Medicine, University Hospital of Messina, Messina, Italy.
Nunziata MorabitoDepartment of Clinical and Experimental Medicine, University Hospital of Messina, Messina, Italy.
Domenico SantoroDepartment of Clinical and Experimental Medicine, University Hospital of Messina, Messina, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is growing interest in the relationship between chronic kidney disease (CKD) and fragility fracture risk. Bone mineral density (BMD) is a major determinant of bone strength, although its role as a predictor of fracture in advanced CKD and hemodialysis is still under debate. We aimed to further investigate surrogates of bone quality and their associations with muscle strength and fracture risk in hemodialysis. Multiple clinical risk factors for fracture and an estimated 10-year probability of fracture, BMD at lumbar spine and femur, trabecular bone score (TBS), X-ray vertebral morphometry, phalangeal bone quantitative ultrasonography (QUS), tibial pulse-echo ultrasonography (PEUS), and handgrip strength were evaluated in a setting of hemodialysis patients in treatment with acetate-free biofiltration (AFB) or bicarbonate hemodialysis. The bone ultrasound measurements, both at phalangeal and tibial sites, were significantly associated with lumbar and femoral DXA values. Handgrip strength was significantly associated with the 10-year probability of fracture (

Indexed as

Fractures, BoneRenal Insufficiency, ChronicBicarbonatesBone DensityCancellous BoneHand StrengthHumansLumbar VertebraeMuscle StrengthRenal DialysisUltrasonographyBicarbonatesbone mineral density (BMD)chronic kidney disease-mineral bone disorder (CKD-MBD)fracturehandgrip strengthhemodialysisosteoporosisquantitative ultrasound (QUS)trabecular bone score (TBS)

Identifiers

PMID36157439
PMCPMC9489856

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.