Evidence map›Paper›PMID 36157418›Full record

ArticleFrontiers in surgery2022

Machine learning for the prediction of acute kidney injury in patients after cardiac surgery.

Xin Xue, Zhiyong Liu, Tao Xue, Wen Chen, Xin Chen

Abstract read
In one paragraph

Article in Frontiers in surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xin XueDepartment of Cardiothoracic Surgery, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China.
Zhiyong LiuDepartment of Cardiothoracic Surgery, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China.
Tao XueDepartment of Cardiothoracic Surgery, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China.
Wen ChenDepartment of Thoracic and Cardiovascular Surgery, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Xin ChenDepartment of Cardiothoracic Surgery, School of Medicine, Southeast University, Nanjing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiac surgery-associated acute kidney injury (CSA-AKI) is the most prevalent major complication of cardiac surgery and exerts a negative effect on a patient's prognosis, thereby leading to mortality. Although several risk assessment models have been developed for patients undergoing cardiac surgery, their performances are unsatisfactory. In this study, a machine learning algorithm was employed to obtain better predictive power for CSA-AKI outcomes relative to statistical analysis. In addition, random forest (RF), logistic regression with LASSO regularization, extreme gradient boosting (Xgboost), and support vector machine (SVM) methods were employed for feature selection and model training. Moreover, the calibration capacity and differentiation ability of the model was assessed using net reclassification improvement (NRI) along with Brier scores and receiver operating characteristic (ROC) curves, respectively. A total of 44 patients suffered AKI after surgery. Fatty acid-binding protein (FABP), hemojuvelin (HJV), neutrophil gelatinase-associated lipocalin (NGAL), mechanical ventilation time, and troponin I (TnI) were correlated significantly with the incidence of AKI. RF was the best model for predicting AKI (Brier score: 0.137, NRI: 0.221), evidenced by an AUC value of 0.858 [95% confidence interval (CI): 0.792-0.923]. Overall, RF exhibited the best performance as compared to other machine learning algorithms. These results thus provide new insights into the early identification of CSA-AKI.

Indexed as

acute kidney injurycardiac surgerymachine learningrandom forestrisk model

Identifiers

PMID36157418
PMCPMC9490319

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.