ArticleFrontiers in surgery2022
Retrospective evaluation of the utility of two-step surgery for facial basal cell carcinoma and squamous cell carcinoma.
Article in Frontiers in surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Microscopically controlled two-step surgery for head and neck non-melanoma skin cancer: the role of primary resection and planned secondary wound closure.Frontiers in oncology · 2026Article
- Outcome of basal cell carcinoma excision with 2 mm surgical margin in Japanese patients: A retrospective study of one-step surgery.JPRAS open · 2025Article
- A comparison of two surgical techniques for basal cell carcinoma of the eyelid: two-step surgery and one-step surgery.International ophthalmology · 2024Article
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7 authors.
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Abstract
In older patients with facial basal cell carcinoma (BCC) or squamous cell carcinoma (SCC), surgery should be aimed to reduce treatment-related sequelae and burden with achieving local tumor care. Therefore, we adopted a two-step surgery (TSS) involving the application of a dermal regeneration template onto the skin defect after tumor resection and subsequent reconstruction by full-thickness skin grafting. We performed a detailed comparison of conventional one-step surgery (OSS) and TSS, including evaluation of local tumor curability, postoperative cosmetic and/or functional impairments, and patient burden. Forty-six patients who underwent TSS and 104 patients treated with OSS were retrospectively investigated. The cohort consisted of 77 men and 73 women (median age, 83 years). The BCC: SCC ratio was 56.7%: 43.3%. The tumor size and excision margin were significantly larger in the TSS group than in the OSS group (
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