Evidence map›Paper›PMID 36157321›Full record

ArticleMolecular and clinical oncology2022

Gastrointestinal stromal tumors in the duodenum show increased contrast enhancement compared with those in the stomach on computed tomography.

Ryosuke Sato, Ryo Harada, Kenji Hashimoto, Tomoaki Tsutsui, Nao Hattori, Masafumi Inoue, Haruhiko Kobashi, Mami Morimoto, Maiko Tamura, Atsushi Hayashi and 1 more

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Article in Molecular and clinical oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Ryosuke SatoDepartment of Gastroenterology and Hepatology, Japanese Red Cross Okayama Hospital, Okayama 700-8607, Japan.
Ryo HaradaDepartment of Gastroenterology and Hepatology, Japanese Red Cross Okayama Hospital, Okayama 700-8607, Japan.
Kenji HashimotoDepartment of Gastroenterology and Hepatology, Japanese Red Cross Okayama Hospital, Okayama 700-8607, Japan.
Tomoaki TsutsuiDepartment of Gastroenterology and Hepatology, Japanese Red Cross Okayama Hospital, Okayama 700-8607, Japan.
Nao HattoriDepartment of Gastroenterology and Hepatology, Japanese Red Cross Okayama Hospital, Okayama 700-8607, Japan.
Masafumi InoueDepartment of Gastroenterology and Hepatology, Japanese Red Cross Okayama Hospital, Okayama 700-8607, Japan.
Haruhiko KobashiDepartment of Gastroenterology and Hepatology, Japanese Red Cross Okayama Hospital, Okayama 700-8607, Japan.
Mami MorimotoDepartment of Radiology, Japanese Red Cross Okayama Hospital, Okayama 700-8607, Japan.
Maiko TamuraDepartment of Radiology, Japanese Red Cross Okayama Hospital, Okayama 700-8607, Japan.
Atsushi HayashiDepartment of Pathology, Japanese Red Cross Okayama Hospital, Okayama 700-8607, Japan.
Masaya IwamuroDepartment of Gastroenterology and Hepatology, Okayama University Hospital, Okayama 700-8558, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Duodenal gastrointestinal stromal tumors (D-GISTs) are a rare and relatively small subset of GISTs whose imaging features are not well known. The present study aimed to evaluate the enhancement pattern of D-GISTs compared with that of gastric GISTs (G-GISTs) using dynamic computed tomography. This single-center, retrospective, clinicopathological analysis was conducted on 10 patients with D-GISTs who underwent surgery between June 2006 and October 2018. In the same period, 25 patients with G-GISTs underwent surgery and were enrolled. The contrast ratio was defined as the ratio between Hounsfield units in contrast enhanced and unenhanced images in different phases, and these ratios were compared between the D-GIST and G-GIST groups. Furthermore, microvessel density, analyzed by immunohistochemical staining for CD31, was compared between the D-GIST and G-GIST groups. The contrast ratio of D-GIST was significantly higher than that of G-GIST in the arterial, portal and delayed phases (P<0.01, P<0.01 and P=0.02, respectively). The microvessel density of the D-GISTs was significantly higher than that of the G-GISTs (P<0.0001). D-GISTs were more hypervascular than G-GISTs on both imaging and pathological analyses.

Indexed as

anti-CD31 antibodyCTGISThypervascularimmunochemistry

Identifiers

PMID36157321
PMCPMC9468842

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