Evidence map›Paper›PMID 36157220›Full record

ArticleDisease markers2022

The Correlation between Endotoxin, D-Lactate, and Diamine Oxidase with Endoscopic Activity in Inflammatory Bowel Disease.

Qi Zhang, Xin Gao, Jixiong Wu, Min Chen

Abstract read
In one paragraph

Article in Disease markers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Tannic acid as a multi-target regulator of intestinal barrier function in livestock.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2026
    Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Challenges in IBD Research 2024: Precision Medicine.Inflammatory bowel diseases · 2024
    Review
  15. Article
  16. Frontiers in immunology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Qi ZhangDepartment of General Medicine, Renmin Hospital of Wuhan University, Wuhan 430060, China.ORCID https://orcid.org/0000-0001-8667-2032
Xin GaoDepartment of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan 430060, China.ORCID https://orcid.org/0000-0001-7198-0163
Jixiong WuDepartment of Gastroenterology, Huanggang Central Hospital, Huanggang 438000, China.ORCID https://orcid.org/0000-0001-6151-5401
Min ChenDepartment of Gastroenterology, Zhongnan Hospital of Wuhan University, Wuhan 430062, China.ORCID https://orcid.org/0000-0001-8248-5408

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Methods: A total of 149 eligible IBD patients including 82 Crohn disease (CD) and 67 Ulcerative colitis (UC) who had received both endoscopic examination and intestinal barrier function detection in our hospital were enrolled in this study. Endoscopic activity was estimated by the Simple Endoscopic Score (SES-CD) for Crohn's Disease and the ulcerative colitis endoscopic index of severity (UCEIS) for ulcerative colitis. The predictive value and optimal predictive thresholds for those biomarkers were determined by receiver operating characteristic analysis. Results: For UC patients, DAO, D-lactate, and ETX showed better correlation with UCEIS than erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) and exhibited satisfactory predictive value in predicting remission. Among patients with CD, DAO and ETX not only showed a better correlation than WBC, ESR, and CRP with SES-CD but also capable to identify more severe patients. Conclusion: DAO and ETX could be used to distinguish different endoscopic activity of CD. DAO, D-lactate, and ETX could predict UC endoscopic remission.

Indexed as

Amine Oxidase (Copper-Containing)Colitis, UlcerativeCrohn DiseaseInflammatory Bowel DiseasesBiomarkersC-Reactive ProteinEndotoxinsFecesHumansLactic AcidSeverity of Illness IndexAmine Oxidase (Copper-Containing)BiomarkersC-Reactive ProteinEndotoxinsLactic Acid

Identifiers

PMID36157220
PMCPMC9507744

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.