Evidence map›Paper›PMID 36157194›Full record

ArticleFrontiers in veterinary science2022

Biopsy and histologic findings of the dura mater at the level of the foramen magnum in 121 CKCS with Chiari-like malformation.

Jaclyn P Holdsworth, Dominic J Marino, Catherine A Loughin, Andrew D Miller, Joseph J Sackman, Martin L Lesser, Marissa O'Donnell

Abstract read
In one paragraph

Article in Frontiers in veterinary science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jaclyn P HoldsworthDepartment of Surgery and the Canine Chiari Institute, Long Island Veterinary Specialists, Plainview, NY, United States.
Dominic J MarinoDepartment of Surgery and the Canine Chiari Institute, Long Island Veterinary Specialists, Plainview, NY, United States.
Catherine A LoughinDepartment of Surgery and the Canine Chiari Institute, Long Island Veterinary Specialists, Plainview, NY, United States.
Andrew D MillerBiomedical Sciences, Section of Anatomic Pathology, College of Veterinary Medicine, Cornell University, Ithaca, NY, United States.
Joseph J SackmanDepartment of Surgery and the Canine Chiari Institute, Long Island Veterinary Specialists, Plainview, NY, United States.
Martin L LesserBiostatistics Unit, Feinstein Institute for Medical Research, Northwell Health, New York, NY, United States.
Marissa O'DonnellDepartment of Surgery and the Canine Chiari Institute, Long Island Veterinary Specialists, Plainview, NY, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To describe histopathologic features found in dural biopsies of Cavalier King Charles Spaniels (CKCS) with Chiari-like malformation (CM) and identify any associations between age, duration of clinical signs, syrinx location or syringomyelia (SM, and quality of life (QOL). The medical records of 121 consecutive client owned CKCS with CM and SM, confirmed by whole body magnetic resonance imaging (MRI), that underwent foramen magnum decompression (FMD) with cranioplasty and durectomy with biopsy from 2006 to 2016 were retrospectively reviewed. Dural biopsies were submitted to a board-certified veterinary pathologist for histopathologic interpretation. The chi-square test was used to analyze associations between histologic findings and categorical variables. For continuous measures, the Kruskal-Wallis non-parametric test was used to compare distributions across pathology categories. A result was considered statistically significant at the

Indexed as

Chiari-like malformationdura histopathologydural biopsyforamen magnum decompressionsyringomyelia

Identifiers

PMID36157194
PMCPMC9489847

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.