Evidence map›Paper›PMID 36157164›Full record

ReviewWorld journal of clinical oncology2022

Nanomedicine approaches for treatment of hematologic and oncologic malignancies.

Polyxeni Nteli, Danae Efremia Bajwa, Dimitrios Politakis, Charalampos Michalopoulos, Anastasia Kefala-Narin, Efstathios P Efstathopoulos, Maria Gazouli

Abstract readReview
In one paragraph

Review in World journal of clinical oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Polyxeni NteliDepartment of Basic Medical Sciences, Medical School, National and Kapodistrian University of Athens, Athens 11527, Greece.
Danae Efremia BajwaDepartment of Basic Medical Sciences, Medical School, National and Kapodistrian University of Athens, Athens 11527, Greece.
Dimitrios PolitakisDepartment of Basic Medical Sciences, Medical School, National and Kapodistrian University of Athens, Athens 11527, Greece.
Charalampos MichalopoulosDepartment of Basic Medical Sciences, Medical School, National and Kapodistrian University of Athens, Athens 11527, Greece.
Anastasia Kefala-NarinDepartment of Basic Medical Sciences, Medical School, National and Kapodistrian University of Athens, Athens 11527, Greece.
Efstathios P Efstathopoulos2Department of Radiology, Medical School, National and Kapodistrian University of Athens, General University Hospital Attikon, Athens12462, Greece.
Maria GazouliDepartment of Basic Medical Sciences, Medical School, National and Kapodistrian University of Athens, Athens 11527, Greece. mgazouli@med.uoa.gr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer is a leading cause of death worldwide. Nowadays, the therapies are inadequate and spur demand for improved technologies. Rapid growth in nanotechnology and novel nanomedicine products represents an opportunity to achieve sophisticated targeting strategies and multi-functionality. Nanomedicine is increasingly used to develop new cancer diagnosis and treatment methods since this technology can modulate the biodistribution and the target site accumulation of chemotherapeutic drugs, thereby reducing their toxicity. Cancer nanotechnology and cancer immunotherapy are two parallel themes that have emerged over the last few decades while searching for a cure for cancer. Immunotherapy is revolutionizing cancer treatment, as it can achieve unprecedented responses in advanced-stage patients, including complete cures and long-term survival. A deeper understanding of the human immune system allows the establishment of combination regimens in which immunotherapy is combined with other treatment modalities (as in the case of the nanodrug Ferumoxytol). Furthermore, the combination of gene therapy approaches with nanotechnology that aims to silence or express cancer-relevant genes

Indexed as

CancerCell therapyGeneImmunotherapyNanomedicine

Identifiers

PMID36157164
PMCPMC9346428

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.