Evidence map›Paper›PMID 36157116›Full record

ArticleWorld journal of gastroenterology2022

Trends in medication use and treatment patterns in Chinese patients with inflammatory bowel disease.

Ling-Ya Yao, Bu-Le Shao, Feng Tian, Mei Ye, Yu-Qin Li, Xiao-Lei Wang, Lin Wang, Shao-Qi Yang, Xiao-Ping Lv, Yan Jia and 4 more

Abstract readMulticenter Study
In one paragraph

Article in World journal of gastroenterology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Trends in the use of biologic agents and their persistence rates in inflammatory bowel disease in India.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2026
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  3. Observational
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  6. Molecules (Basel, Switzerland) · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Ling-Ya YaoDepartment of Gastroenterology, Sir Run Run Shaw Hospital, College of Medicine Zhejiang University, Hangzhou 310016, Zhejiang Province, China.
Bu-Le ShaoDepartment of Gastroenterology, Sir Run Run Shaw Hospital, College of Medicine Zhejiang University, Hangzhou 310016, Zhejiang Province, China.
Feng TianDepartment of Gastroenterology, Shengjing Hospital of China Medical University, Shenyang 110000, Liaoning Province, China.
Mei YeDepartment of Gastroenterology, Zhongnan Hospital of Wuhan University, Wuhan 430000, Hubei Province, China.
Yu-Qin LiDepartment of Gastroenterology, Bethune First Affiliated Hospital of Jilin University, Changchun 130000, Jilin Province, China.
Xiao-Lei WangDepartment of Gastroenterology, Shanghai 10 People's Hospital, Tongji University, Shanghai 200072, China.
Lin WangDepartment of Gastroenterology, Zhongshan Hospital Affiliated to Xiamen University, Xiamen 361000, Fujian Province, China.
Shao-Qi YangDepartment of Gastroenterology, General Hospital of Ningxia Medical University, Yinchuan 750004, Ningxia Hui Autonomous Region, China.
Xiao-Ping LvDepartment of Gastroenterology, The First Affiliated Hospital of Guangxi Medical University, Nanning 530000, Guangxi Zhuang Autonomous Region, China.
Yan JiaDepartment of Gastroenterology, The 7 Medical Center of Chinese PLA General Hospital, Beijing 100000, China.
Xue-Hong WangDepartment of Gastroenterology, Second Xiangya Hospital, Changsha 410011, Hunan Province, China.
Xiao-Qi ZhangDepartment of Gastroenterology, Nanjing Drum Tower Hospital, Nanjing 210000, Jiangsu Province, China.
Yan-Ling WeiDepartment of Gastroenterology, Daping Hospital, Army Medical University, Chongqing 400000, China.
Qian CaoDepartment of Gastroenterology, Sir Run Run Shaw Hospital, College of Medicine Zhejiang University, Hangzhou 310016, Zhejiang Province, China. caoq@zju.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMedications for inflammatory bowel disease (IBD) have changed dramatically over time. However, no study on long-term medication profiles has been conducted in the Chinese population.

aimTo evaluate temporal changes in medication use and treatment patterns for Chinese patients with IBD.

methodsA multicenter retrospective cohort study was conducted among Chinese patients newly diagnosed with Crohn's disease (CD) and ulcerative colitis (UC) between January 1999 and December 2019. Baseline characteristics and drug prescriptions were collected. Trends in medication use and therapeutic patterns were analyzed.

resultsIn total, 3610 patients were analyzed. During follow-up, 5-aminosalicylates (5-ASA) and corticosteroids (CS) prescriptions gradually decreased, accompanied by a notable increase in immunosuppressants (IMS) and infliximab (IFX) prescriptions in patients with CD. Prescription rates of 5-ASA and CS were stable, whereas IMS and IFX slightly increased since 2007 in patients with UC. Subgroup (

conclusionLong-term treatment strategies analyses has provided unique insight into the switch from conventional drugs to IFX in Chinese patients with CD.

Indexed as

Colitis, UlcerativeCrohn DiseaseInflammatory Bowel DiseasesAdrenal Cortex HormonesChinaChronic DiseaseHumansImmunosuppressive AgentsInfliximabMesalamineRetrospective StudiesAdrenal Cortex HormonesImmunosuppressive AgentsInfliximabMesalamineCrohn's diseaseInflammatory bowel diseaseInfliximabMedication trendsTreatment patternUlcerative colitis

Identifiers

PMID36157116
PMCPMC9403423

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.