ArticleThe International journal of angiology : official publication of the International College of Angiology, Inc2022
Pathophysiology and Management of Pulmonary Embolism.
Article in The International journal of angiology : official publication of the International College of Angiology, Inc, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 35 citations in OpenAlex.
- Severe Biventricular Takotsubo Syndrome Triggered by Status Epilepticus With Pulmonary Embolism and Critical Illness Myopathy.JACC. Case reports · 2026Article
- Nomogram-Based Mortality Prediction in Acute Pulmonary Embolism Using Inflammatory Biomarkers and the Simplified Pulmonary Embolism Severity Index.Journal of clinical medicine · 2026Article
- Pulmonary embolism mortality in the United States: a nationwide analysis.Journal of thrombosis and thrombolysis · 2026Article
- Values of D-dimer, APTT, PT and INR in distinguishing between acute ischemic stroke patients with and without non-valvular atrial fibrillation.Journal of medical biochemistry · 2026Article
- Perioperative Diagnosis of Acute Pulmonary Embolism Following Laparoscopic Hysterectomy Under General Anaesthesia: A Rare Case Report.Turkish journal of anaesthesiology and reanimation · 2026Article
- Albumin-Bilirubin and Platelet-Albumin-Bilirubin scores as predictors of all-cause long-term mortality in intermediate-high-risk pulmonary embolism.Irish journal of medical science · 2026Article
- Article
- Pulmonary Embolism in Acute Ischaemic Stroke: Evolving Evidence, Diagnostic Challenges, and a Novel Thromboinflammatory Axis Hypothesis.International journal of molecular sciences · 2025Review
- Hemodynamic improvement with Impella RP in acute massive pulmonary embolism: a narrative review of cardiovascular outcomes and pulmonary catheter pressure assessment.Annals of medicine and surgery (2012) · 2025Review
- Catestatin in Cardiovascular Diseases.International journal of molecular sciences · 2025Review
- Prevalence and clinical burden of venous thromboembolic events (VTEs) in contemporary total knee arthroplasties (TKAs) in US hospitals.Journal of orthopaedics · 2025Article
- Venous Thromboembolism: Current Insights and Future Directions.The International journal of angiology : official publication of the International College of Angiology, Inc · 2024Review
- Exploring varied radiologic appearance in pulmonary embolism with CT pulmonary angiography: Case series with literature review.Radiology case reports · 2024Article
- Diagnostic Strategies in Pulmonary Embolism.The International journal of angiology : official publication of the International College of Angiology, Inc · 2024Review
- Epidemiology, Etiology, and Pathophysiology of Pulmonary Embolism.The International journal of angiology : official publication of the International College of Angiology, Inc · 2024Review
- Pulmonary Embolism in Donor Lungs-Incidence and Management.The International journal of angiology : official publication of the International College of Angiology, Inc · 2024Review
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pulmonary embolism (PE) is one of the most common etiologies of cardiovascular mortality. It could be linked to several risk factors including advanced age. The pathogenesis of PE is dictated by the Virchow's triad that includes venous stasis, endothelial injury, and a hypercoagulable state. The diagnosis of PE is difficult and is often missed due to the nonspecific symptomatology. Hypoxia is common in the setting of PE, and the degree of respiratory compromise is multifactorial and influenced by underlying cardiac function, clot location, and ability to compensate with respiratory mechanics. Right ventricular dysfunction/failure is the more profound cardiovascular impact of acute PE and occurs due to sudden increase in afterload. This is also the primary cause of death in PE. High clinical suspicion is required in those with risk factors and presenting signs or symptoms of venous thromboembolic disease, with validated clinical risk scores such as the Wells, Geneva, and pulmonary embolism rule out criteria in estimating the likelihood for PE. Advancement in capture time and wider availability of computed tomographic pulmonary angiography and D-dimer testing have further facilitated the rapid evaluation and diagnosis of suspected PE. Treatment is dependent on clinical presentation and initially involves providing adequate oxygenation and stabilizing hemodynamics. Anticoagulant therapy is indicated for the treatment of PE. Treatment is guided by presence or absence of shock and ranges from therapeutic anticoagulation to pharmacologic versus mechanical thrombectomy. The prognosis of patients can vary considerably depending on the cardiac and pulmonary status of patient and the size of the embolus.
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