ArticleWorld journal of gastroenterology2022
Prevalence and factors associated with vitamin C deficiency in inflammatory bowel disease.
Article in World journal of gastroenterology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Diet-derived circulating antioxidants and risk of inflammatory bowel disease: a Mendelian randomization study and meta-analysis.Frontiers in immunology · 2024Pooled it
- Gut Microbiota Remodeling Mediates the Therapeutic Effects of a Plant-Based Medicine on DSS-Induced Ulcerative Colitis in Mice via the Butyrate-SVCT1-Vitamin C Axis.International journal of molecular sciences · 2026Article
- Low Vitamin D and C Levels are Associated with Increased Disease Activity in Jordanian RA and SLE Patients: A Case-Control StudyEndocrine, metabolic & immune disorders drug targets · 2026Article
- Metabolomics reveal distinct molecular pathways associated with future risk of Crohn's Disease.Gut microbes · 2025Article
- Network-Based Multiomic Nutrient-Associated Predictive Models for Inflammatory Bowel Disease.Current developments in nutrition · 2025Article
- Vitamin C status across the spectrum of chronic kidney disease and healthy controls: a cross-sectional study.The American journal of clinical nutrition · 2025Article
- The Community Prevalence of Vitamin C Deficiency and Inadequacy-How Does Australia Compare With Other Nations? A Scoping Review.Health science reports · 2025Review
- Review
- The Prevalence, Risk Factors, and Clinical Outcomes of Vitamin C Deficiency in Adult Hospitalised Patients: A Retrospective Observational Study.Nutrients · 2025Observational
- The Evolving Guidelines on Fiber Intake for Patients with Inflammatory Bowel Disease; From Exclusion to Texture Modification.Current gastroenterology reports · 2025Review
- Association between vitamin C, D, and K intake and inflammatory bowel disease risk: findings from 2009 to 2010 NHANES.BMC gastroenterology · 2025Article
- Micronutrient-deficient diets and possible environmental enteric dysfunction in Buruli ulcer endemic communities in Ghana: Lower dietary diversity and reduced serum zinc and vitamin C implicate micronutrient status a possible susceptibility factor.PLoS neglected tropical diseases · 2025Article
- Scurvy as a Cause of Leg Pain and Limp in Pediatric and Adolescent Patients.Journal of the Pediatric Orthopaedic Society of North America · 2025Review
- Method of oral delivery affects vitamin C-mediated alleviation of colitis in a mouse model.Gut microbes reports · 2025Article
- Prevalence, risk factors, and clinical outcomes of vitamin C deficiency in adult hospitalized patients in high-income countries: a scoping review.Nutrition reviews · 2024Article
- The Troubling Rise of Scurvy: A Review and National Analysis of Incidence, Associated Risk Factors, and Clinical Manifestations.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2024Review
- Article
- What Do We C in Children With Scurvy? A Case Series Focused on Musculoskeletal Symptoms.Hospital pediatrics · 2024Article
- Article
- Avoiding food avoidance in patients with inflammatory bowel disease.United European gastroenterology journal · 2023Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPatients with inflammatory bowel disease (IBD) are prone to several nutritional deficiencies. However, data are lacking on vitamin C deficiency in Crohn's disease (CD) and ulcerative colitis (UC) patients, as well as the impact of clinical, biomarker and endoscopic disease severity on the development of vitamin C deficiency.
aimTo determine proportions and factors associated with vitamin C deficiency in CD and UC patients.
methodsIn this retrospective study, we obtained clinical, laboratory and endoscopic data from CD and UC patients presenting to the IBD clinic at a single tertiary care center from 2014 to 2019. All patients had an available plasma vitamin C level. Of 353 subjects who met initial search criteria using a cohort discovery tool, 301 ultimately met criteria for inclusion in the study. The primary aim described vitamin C deficiency (≤ 11.4 μmol/L) rates in IBD. Secondary analyses compared proportions with deficiency between active and inactive IBD. Multivariate logistic regression analysis evaluated factors associated with deficiency.
resultsOf 301 IBD patients, 21.6% had deficiency, including 24.4% of CD patients and 16.0% of UC patients. Patients with elevated C-reactive protein (CRP) (39.1%
conclusionVitamin C deficiency was common in IBD. Patients with elevated inflammatory markers and penetrating disease had higher rates of vitamin C deficiency.
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