Evidence map›Paper›PMID 36156887›Full record

ArticleAmerican heart journal plus : cardiology research and practice2022

Medical therapy for patients with recent-onset heart failure with reduced ejection fraction during the COVID-19 pandemic: Insights from the Veteran's affairs healthcare system.

Alexander T Sandhu, Jimmy Zheng, Rebecca L Tisdale, Shun Kohsaka, Mintu P Turakhia, Paul A Heidenreich

Open access · goldAbstract read
In one paragraph

Article in American heart journal plus : cardiology research and practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Alexander T SandhuDivision of Cardiovascular Medicine, Department of Medicine, Stanford University, Stanford, CA, United States of America.
Jimmy ZhengStanford University School of Medicine, Stanford, CA, United States of America.
Rebecca L TisdaleMedical Service, VA Palo Alto Health Care System, Palo Alto, CA, United States of America.
Shun KohsakaDepartment of Cardiology, Keio University School of Medicine, Tokyo, Japan.
Mintu P TurakhiaDivision of Cardiovascular Medicine, Department of Medicine, Stanford University, Stanford, CA, United States of America.
Paul A HeidenreichDivision of Cardiovascular Medicine, Department of Medicine, Stanford University, Stanford, CA, United States of America.
Stanford University · USKeio University · JPVA Palo Alto Health Care System · US

Funding

The Effect of Value-based Payment on Heart Failure Quality of Care (Value-HF)K23HL151672 · NHLBI · STANFORD UNIVERSITY · PI SANDHU, ALEXANDER · 2020 to 2024
$854k
NHLBI NIH HHS K23 HL151672
6 · The paper itself

Abstract

This study aims to evaluate trends in guideline-directed medical therapy (GDMT) for patients with recent-onset heart failure with reduced ejection fraction (HFrEF) following the onset of the COVID-19 pandemic using an interrupted time series analysis in the Veteran's Affairs Healthcare System. Among 71,428 patients with recent-onset HFrEF between 1/1/2018 and 2/28/2021, we found the pandemic was not associated with differences in treatment rates for beta-blockers, renin-angiotensin-aldosterone system inhibitors, or mineralocorticoid receptor antagonists; there was a 2.6 % absolute decrease (95 % CI: 0.5 %-4.7 %) in ARNI rates in April 2020; which decreased over the pandemic. Despite the changes to healthcare delivery, the COVID-19 pandemic was associated with minimal changes in GDMT rates among patients with recent-onset HFrEF.

Indexed as

Covid-19Heart failureMedical therapyQuality of care

Identifiers

PMID36156887
PMCPMC9481472
OpenAlexW4296183693

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.