ArticlePediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology2022
Relevance of sensitization to legumes in peanut-allergic children.
Article in Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- IgE-Mediated Legume Allergy in Children: Insights from a Single-Center Experience in Italy.Nutrients · 2026Article
- Heat Processing Reduces IgE Binding but Not Basophil Sensitivity to Pea Proteins in Pea-Allergic Children.Nutrients · 2026Article
- Cumin anaphylaxis and allergy to spices in pediatrics: a case report and literature review.Frontiers in immunology · 2026Review
- Allergens from plant-based food allergen sources and their clinical and diagnostic relevance.Allergologie select · 2026Review
- Experts' perspectives on allergic reactions to emerging food sources, pollen and insects.Allergologie select · 2026Article
- The prevalence of outgrowing non-priority legume allergies in children.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2025Article
- Food Anaphylaxis: Eight Food Allergens Without Mandatory Labelling Highlighted by the French Allergy-Vigilance Network.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2025Article
- Traditional and Emerging Physical Processing Technologies: Applications and Challenges in Allergen Control of Animal and Plant Proteins.Comprehensive reviews in food science and food safety · 2025Review
- Legume Allergens Pea, Chickpea, Lentil, Lupine and Beyond.Current allergy and asthma reports · 2024Review
- IgE-Mediated Legume Allergy: A Pediatric Perspective.Journal of personalized medicine · 2024Review
- Fenugreek allergy caused by cross-reactivity with peanut: AnThe journal of allergy and clinical immunology. Global · 2024Article
- Rare causes of pediatric anaphylaxis due to obscure allergens.Frontiers in allergy · 2024Review
- "Climate-friendly" diets from an allergy point of view.Allergologie select · 2024Review
- Peanut Allergy and Component-Resolved Diagnostics Possibilities-What Are the Benefits?Nutrients · 2023Review
- Lupin allergy: Another member of the peanut gallery?Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2023Article
- Vegan diets from an allergy point of view - Position paper of the DGAKI working group on food allergy.Allergologie select · 2023Article
- Immune signatures predicting the clinical outcome of peanut oral immunotherapy: where we stand.Frontiers in allergy · 2023Review
- Relevance of sensitization to legumes in peanut-allergic children.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2022Article
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8 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundLegume consumption has increased during the two past decades. In France, legumes are responsible for 14.6% of food-related anaphylaxis in children, with peanut as the main allergen (77.5%). Few studies have demonstrated cross-reactivities between peanut and other legumes. The aim of this study was to determine prevalence and relevance of sensitization to legumes in peanut-allergic children.
methodsAll children, aged of 1-17 years, admitted to the Pediatric Allergy Department of the University Hospital of Nancy between January 1, 2017 and February 29, 2020 with a confirmed peanut allergy (PA) and a documented consumption or sensitization to at least one other legume were included. Data were retrospectively collected regarding history of consumption, skin prick tests, specific immunoglobulin E (IgE), prior allergic reactions, and oral food challenges for each legume.
resultsAmong the 195 included children with PA, 122 were sensitized to at least one other legume (63.9%). Main sensitizations were for fenugreek (N = 61, 66.3%), lentil (N = 38, 42.2%), soy (N = 61, 39.9%), and lupine (N = 63, 34.2%). Among the 122 sensitized children, allergy to at least one legume was confirmed for 34 children (27.9%), including six children who had multiple legume allergies (4.9%). Lentil, lupine, and pea were the main responsible allergens. Half of allergic reactions to legumes other than peanut were severe.
conclusionThe high prevalence of legume sensitization and the frequent severe reactions reported in children with PA highlight that tolerated legume consumption should be explored for each legume in the case of PA, and sensitization should be investigated if not.
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