Evidence map›Paper›PMID 36156456›Full record

Trial reportObesity (Silver Spring, Md.)2022

The use of virtual visits for obesity pharmacotherapy in patients with overweight or obesity compared with in-person encounters.

Marcio L Griebeler, W Scott Butsch, Paloma Rodriguez, Laura Lomeli, Matthew Kampert, Vinni Makin, Ula Abed Alwahab, Elena Borukh, Erin Daigle, James Bena and 2 more

Abstract readRandomized Controlled TrialEquivalence Trial
In one paragraph

Trial report in Obesity (Silver Spring, Md.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Adherence to Behavioral Weight Management: A Scoping Review of Definitions, Measurement, and Components.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026
    Article
  5. Review
  6. Article
  7. Observational
  8. Review
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Marcio L GriebelerEndocrinology and Metabolism Institute, Cleveland Clinic Foundation, Cleveland, Ohio, USA.ORCID 0000-0001-5723-1182
W Scott ButschBariatric and Metabolic Department, Cleveland Clinic Foundation, Cleveland, Ohio, USA.ORCID 0000-0001-7137-9423
Paloma RodriguezEndocrinology and Metabolism Institute, Cleveland Clinic Foundation, Cleveland, Ohio, USA.
Laura LomeliEndocrinology and Metabolism Institute, Cleveland Clinic Foundation, Cleveland, Ohio, USA.
Matthew KampertEndocrinology and Metabolism Institute, Cleveland Clinic Foundation, Cleveland, Ohio, USA.
Vinni MakinEndocrinology and Metabolism Institute, Cleveland Clinic Foundation, Cleveland, Ohio, USA.
Ula Abed AlwahabEndocrinology and Metabolism Institute, Cleveland Clinic Foundation, Cleveland, Ohio, USA.
Elena BorukhEndocrinology and Metabolism Institute, Cleveland Clinic Foundation, Cleveland, Ohio, USA.
Erin DaigleEndocrinology and Metabolism Institute, Cleveland Clinic Foundation, Cleveland, Ohio, USA.
James BenaDepartment of Quantitative Health Sciences, Cleveland Clinic Foundation, Cleveland, Ohio, USA.
Kevin M PantaloneEndocrinology and Metabolism Institute, Cleveland Clinic Foundation, Cleveland, Ohio, USA.
Bartolome BurgueraEndocrinology and Metabolism Institute, Cleveland Clinic Foundation, Cleveland, Ohio, USA.ORCID 0000-0001-9808-8327

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aimed to demonstrate noninferiority using telehealth in treating obesity with phentermine in patients with BMI ≥ 27 kg/m

methodsA 12-week, randomized, prospective, single-center, open label trial compared the use of virtual visits versus in-person visits for the treatment of obesity using phentermine. The primary end point was percentage mean change in body weight from baseline to 12 weeks. A noninferiority approach assuming a 3% noninferiority region was used to assess effect size differences.

resultsThe weight loss in the virtual visit arm was noninferior to the in-person arm at all time points. At 12 weeks, the mean change in weight was -6.5% among the virtual group and -7.7% among the in-person group. In addition, 65% of virtual patients and 71% of in-person patients demonstrated a weight reduction of at least 5%. There was no difference in medication tolerance, adherence, and compliance.

conclusionsThese results indicate that the virtual obesity pharmacotherapy visits in adults aged 18 to 65 years prescribed phentermine are effective and noninferior in achieving meaningful weight loss after 12 weeks. Future clinical trials are needed to better assess the effectiveness of televisits for obesity pharmacotherapy.

Indexed as

ObesityOverweightAdultHumansPhentermineProspective StudiesWeight LossPhentermine

Identifiers

PMID36156456
PMCPMC9826334

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.