Evidence map›Paper›PMID 36155499›Full record

ArticleJournal of back and musculoskeletal rehabilitation2023

The association between paraspinal muscle degeneration and osteoporotic vertebral compression fracture severity in postmenopausal women.

Wei Huang, Xian-Hua Cai, Yi-Rong Li, Feng Xu, Xin-Hao Jiang, Dan Wang, Min Tu

Open access · bronzeAbstract read
In one paragraph

Article in Journal of back and musculoskeletal rehabilitation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
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  4. Effects of paraspinal muscle atrophy and fatty degeneration on segmental kyphosis after conservative treatment of osteoporotic vertebral compression fracture (OVCF) in postmenopausal women.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Wei HuangHubei University of Chinese Medicine, Wuhan, China.
Xian-Hua CaiHubei University of Chinese Medicine, Wuhan, China.
Yi-Rong LiDepartment of Spine Surgery, Jingmen No. 2 People's Hospital, Jingmen, Wuhan, China.
Feng XuDepartment of Orthopedics, PLA Middle Military Command General Hospital, Wuhan, China.
Xin-Hao JiangDepartment of Spine Surgery, Jingmen No. 2 People's Hospital, Jingmen, Wuhan, China.
Dan WangDepartment of Spine Surgery, Jingmen No. 2 People's Hospital, Jingmen, Wuhan, China.
Min TuDepartment of Spine Surgery, Jingmen No. 2 People's Hospital, Jingmen, Wuhan, China.
First People’s Hospital of Jingmen · CNHubei University of Chinese Medicine · CNWuhan General Hospital of Guangzhou · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAccording to reports in the literature, osteoporotic vertebral compression fracture (OVCF) is associated with paraspinal muscle degeneration; however, the association between the severity of OVCF and paraspinal muscle degeneration is not clear.

objectiveThe purpose of this study was to investigate the association between paraspinal muscle degeneration and OVCF severity in postmenopausal women.

methodsThree hundred and seventy-six MRI images from 47 patients were collected and analyzed. Sagittal and axial coronal T2-weighted images were used to measure the fractured vertebra sagittal cross-sectional area (FSCSA), the adjacent normal vertebral body sagittal cross-sectional area (NSCSA), paraspinal muscle cross-sectional area (CSA), and the fat cross-sectional area (FCSA). The ratio of fractured vertebra compressed sagittal cross-sectional area (RCSA) and fatty infiltration ratio (FIR) was subsequently calculated. The formulas for RCSA and FIR calculations are as follows: RCSA = (NSCSA-FSCSA)/NSCSA; FIR = FCSA/CSA. RCSA and FIR represent the severity of OVCF and paraspinal muscle degeneration, respectively.

resultsThe correlation between paraspinal muscle degeneration and OVCF severity was analyzed using the Pearson correlation, and multiple regression analysis was performed to explore related risk factors. OVCF severity was closely associated with paraspinal muscle degeneration (L3/4 FIR r= 0.704, P< 0.05; L4/5 FIR r= 0.578, P< 0.05; L5/S1 FIR r= 0.581, P< 0.05). Multiple regression analysis demonstrated that the risk factor for OVCF severity was L3/4 FIR (β= 0.421, P= 0.033).

conclusionOVCF severity was associated with the FIR of paraspinal muscles, and L3/4 FIR was a predictive factor for OVCF severity in postmenopausal women.

Indexed as

Fractures, CompressionSpinal FracturesFemaleHumansLumbar VertebraeMagnetic Resonance ImagingMuscular AtrophyParaspinal MusclesPostmenopauseRetrospective Studiesfatty infiltrationOsteoporosisparaspinal musclepostmenopausal womenvertebral fracture

Identifiers

PMID36155499
PMCPMC10041424
OpenAlexW4296492832

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.