Evidence map›Paper›PMID 36155119›Full record

Trial reportArchives of endocrinology and metabolism2022

Curcumin supplementation reduces blood glucose and serum lipids of Brazilian women with high waist circumference: a randomized clinical trial.

Pamela Cristina de Sousa Guardiano Reis, Ana Gabriella Pereira Alves, Lídia Andreu Guillo, Menandes Alves de Sousa, Neidiane Rosa Trindade, Maria Sebastiana Silva

Open access · diamondAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Archives of endocrinology and metabolism, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

  1. Trial
  2. Clinical Potential ofFoods (Basel, Switzerland) · 2025
    Review
  3. Review
  4. The Potential Systemic Anti-Inflammatory Effect of Turmeric Dried Extract.Endocrine, metabolic & immune disorders drug targets · 2025
    Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Pamela Cristina de Sousa Guardiano ReisLaboratório de Fisiologia, Nutrição e Saúde (LAFINS), Faculdade de Educação Física e Dança (FEFD), Universidade Federal de Goiás (UFG) - Campus Samambaia, Goiânia, Goiás, Brasil.
Ana Gabriella Pereira AlvesLaboratório de Fisiologia, Nutrição e Saúde (LAFINS), Faculdade de Educação Física e Dança (FEFD), Universidade Federal de Goiás (UFG) - Campus Samambaia, Goiânia, Goiás, Brasil, anagabriela_alves@hotmail.com.
Lídia Andreu GuilloInstituto de Ciências Biológicas, Departamento de Bioquímica e Biologia Molecular, Universidade Federal de Goiás (UFG) - Campus Samambaia, Goiânia, Goiás, Brasil.
Menandes Alves de SousaLaboratório de Fisiologia, Nutrição e Saúde (LAFINS), Faculdade de Educação Física e Dança (FEFD), Universidade Federal de Goiás (UFG) - Campus Samambaia, Goiânia, Goiás, Brasil.
Neidiane Rosa TrindadeLaboratório de Fisiologia, Nutrição e Saúde (LAFINS), Faculdade de Educação Física e Dança (FEFD), Universidade Federal de Goiás (UFG) - Campus Samambaia, Goiânia, Goiás, Brasil.
Maria Sebastiana SilvaLaboratório de Fisiologia, Nutrição e Saúde (LAFINS), Faculdade de Educação Física e Dança (FEFD), Universidade Federal de Goiás (UFG) - Campus Samambaia, Goiânia, Goiás, Brasil.
Universidade Federal de Goiás · BRInstituto de Ciencias Tecnológicas · CL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To evaluate the effect of curcumin supplementation on the body compositions and biochemical parameters of Brazilian women with high waist circumferences. Methods: This is a blind, randomized, placebo-controlled clinical trial conducted in 2016 with 35 Brazilian women with high waist circumference (WC). In total, 80 participants were randomized [38 in the placebo group (PG) and 42 in the supplemented group (SG)], but at the end of the protocol, 20 individuals in the PG and 15 in the SG were evaluated. The sample consumed one capsule of curcumin (500 mg/day) (Curcumin C3 Complex®) or a placebo for 90 days. Body weight, height, body mass index, WC, body fat, fat free mass, fasting glucose (FG), lipid profile [triglycerides (TGs), total cholesterol (TC), HDL-c and LDL-c], physical activity level and food intake (energy, carbohydrate, total fat and protein) data were evaluated before and after the intervention. Results: Curcumin supplementation reduced body mass (p < 0.040) but did not alter other anthropometric parameters or body composition (p ≥ 0.050). In relation to the biochemical profile, the SG saw reductions in FG (p < 0.001), TGs (p < 0.001) and TC (p = 0.001) compared with the PG. At the baseline and during the intervention, the practice of physical activity and food intake did not differ between the SG and PG (p ≥ 0.050). Conclusion: Curcumin supplementation improved the blood glucose and lipid profile of Brazilian women with high WC, without altering body composition. New studies with larger sample sizes and longer durations are important for identifying more robust data regarding the proposal of this work.

Indexed as

Blood GlucoseCurcuminBody Mass IndexBrazilCholesterol, HDLDietary SupplementsFemaleHumansTriglyceridesWaist CircumferenceBlood GlucoseCholesterol, HDLCurcuminTriglyceridesblood glucosecholesterolCurcumintriglycerideswomen

Identifiers

PMID36155119
PMCPMC10118764
OpenAlexW4297248870

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.