Evidence map›Paper›PMID 36154936›Full record

ArticleBMC palliative care2022

Availability of and factors related to interventional procedures for refractory pain in patients with cancer: a nationwide survey.

Yuko Uehara, Yoshihisa Matsumoto, Toshifumi Kosugi, Miyuki Sone, Naoki Nakamura, Akio Mizushima, Mitsunori Miyashita, Tatsuya Morita, Takuhiro Yamaguchi, Eriko Satomi

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in BMC palliative care, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06978673 (Comparison of Neurolytic Block Techniques for the Treatment of Abdominal Visceral Pain and Their Influence On The Quality of Life of Patients With Cancer), which is not on this map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06978673 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Comparison of Neurolytic Block Techniques for the Treatment of Abdominal Visceral Pain and Their Influence On The Quality of Life of Patients With Cancer

TypeinterventionalSponsorInstituto do Cancer do Estado de São PauloRan2025 to 2026Enrolled64ConditionsCancer, Malignant Tumors, Abdominal Cancer, Cancer Pain, Visceral PainArmsSplanchnic nerve neurolysis - 5 ml of absolute alcohol (100%), Celiac Plexus Neurolysis - 5 ml of absolute alcohol (100%)
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 3 countries.

Yuko UeharaDepartment of Palliative Medicine, Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo, 113-8421, Japan.
Yoshihisa MatsumotoDepartment of Palliative Medicine, Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo, 113-8421, Japan. yosmatsu@east.ncc.go.jp.ORCID http://orcid.org/0000-0003-3112-4818
Toshifumi KosugiDepartment of Palliative Care, Saga-ken Medical Centre Koseikan, Saga, Japan; 400 Kasemachinakabaru, Saga, Saga, 840-8571, Japan.
Miyuki SoneDepartment of Diagnostic Radiology/Interventional Radiology Center, National Cancer Center Hospital, Tokyo, Japan; 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.
Naoki NakamuraDepartment of Radiology, St. Marianna University School of Medicine, Kawasaki, Japan; 2-16-1 Sugao, Miyamae-ku, Kawasaki, Kanagawa, 216-8511, Japan.
Akio MizushimaDepartment of Palliative Medicine, Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo, 113-8421, Japan.
Mitsunori MiyashitaDepartment of Palliative Nursing, Health Sciences, Tohoku University Graduate School of Medicine, Sendai, Japan; 2-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi, 980-8575, Japan.
Tatsuya MoritaDivision of Supportive and Palliative Care, Seirei Mikatahara General Hospital, Hamamatsu, Japan; 3453 Mikatahara-cho, Hamamatsu, Shizuoka, 433-8558, Japan.
Takuhiro YamaguchiDivision of Biostatistics, Tohoku University School of Medicine, Sendai, Japan; 2-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi, 980-8575, Japan.
Eriko SatomiDepartment of Palliative Medicine, Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo, 113-8421, Japan.ORCID http://orcid.org/0000-0003-1516-2849
Juntendo University · JPTohoku University · JPNational Cancer Centre Japan · JPSaga-Ken Medical Centre Koseikan · JPSeirei Mikatabara General Hospital · JPSt. Marianna University School of Medicine · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCancer pain may be refractory to standard pharmacological treatment. Interventional procedures are important for quality of analgesia. The aim of the present study was to clarify the availability of four interventional procedures (celiac plexus neurolysis/splanchnic nerve neurolysis, phenol saddle block, epidural analgesia, and intrathecal analgesia), the number of procedures performed by specialists, and their associated factors. In addition, we aimed to establish how familiar home hospice physicians and oncologists are with the different interventional procedures available to manage cancer pain.

methodsA cross-sectional survey using a self-administered questionnaire was conducted. Subjects were certified pain specialists, interventional radiologists, home hospice physicians, and clinical oncologists.

resultsThe numbers of valid responses/mails were 545/1,112 for pain specialists, 554/1,087 for interventional radiology specialists, 144/308 for home hospice physicians, and 412/800 for oncologists. Among pain specialists, depending on intervention, 40.9-75.2% indicated that they perform each procedure by themselves, and 47.5-79.8% had not performed any of the procedures in the past 3 years. Pain specialists had performed the four procedures 4,591 times in the past 3 years. Among interventional radiology specialists, 18.1% indicated that they conduct celiac plexus neurolysis/splanchnic nerve neurolysis by themselves. Interventional radiology specialists had performed celiac plexus neurolysis/splanchnic nerve neurolysis 202 times in the past 3 years. Multivariate analysis revealed that the number of patients seen for cancer pain and the perceived difficulty in gaining experience correlated with the implementation of procedures among pain specialists. Among home hospice physicians and oncologists, depending on intervention, 3.5-27.1% responded that they were unfamiliar with each procedure.

conclusionsAlthough pain specialists responded that the implementation of each intervention was possible, the actual number of the interventions used was limited. As interventional procedures are well known, it is important to take measures to ensure that pain specialists and interventional radiology physicians are sufficiently utilized to manage refractory cancer pain.

Indexed as

Cancer PainCeliac PlexusIntractable PainNeoplasmsCross-Sectional StudiesHumansPhenolsSurveys and QuestionnairesPhenolsAvailabilityInterventional proceduresNationwide surveyRefractory cancer painRelated factors

Identifiers

PMID36154936
PMCPMC9511722
OpenAlexW4297145529

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.