Evidence map›Paper›PMID 36154880›Full record

ReviewBiochemistry. Biokhimiia2022

Will Peptides Help to Stop COVID-19?

Viktoriya G Krut', Sergei A Chuvpilo, Irina V Astrakhantseva, Liubov I Kozlovskaya, Grigory A Efimov, Andrei A Kruglov, Marina S Drutskaya, Sergei A Nedospasov

Open access · bronzeAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Biochemistry. Biokhimiia, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Viktoriya G Krut'Sirius University of Science and Technology, Federal Territory Sirius, Krasnodar Krai, 354340, Russia.
Sergei A ChuvpiloSirius University of Science and Technology, Federal Territory Sirius, Krasnodar Krai, 354340, Russia.
Irina V AstrakhantsevaSirius University of Science and Technology, Federal Territory Sirius, Krasnodar Krai, 354340, Russia.
Liubov I KozlovskayaChumakov Federal Scientific Center for Research and Development of Immunobiological Products, Russian Academy of Sciences, Moscow, 108819, Russia.
Grigory A EfimovNational Medical Research Center of Hematology, Ministry of Health of the Russian Federation, Moscow, 125167, Russia.
Andrei A KruglovBelozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, 119234, Russia.
Marina S DrutskayaSirius University of Science and Technology, Federal Territory Sirius, Krasnodar Krai, 354340, Russia.
Sergei A NedospasovSirius University of Science and Technology, Federal Territory Sirius, Krasnodar Krai, 354340, Russia. sergei.nedospasov@gmail.com.
Sirius University of Science and Technology · RUEngelhardt Institute of Molecular Biology · RULomonosov Moscow State University · RUNational Medical Research Center of Cardiology · RURussian Academy of Sciences · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peptides are widely used for the diagnostics, prevention, and therapy of certain human diseases. How useful can they be for the disease caused by the SARS-CoV-2 coronavirus? In this review, we discuss the possibility of using synthetic and recombinant peptides and polypeptides for prevention of COVID-19 via blocking the interaction between the virus and its main receptor ACE2, as well as components of antiviral vaccines, in particular, against new emerging virus variants.

Indexed as

COVID-19Angiotensin-Converting Enzyme 2Antiviral AgentsHumansPeptidesSARS-CoV-2Angiotensin-Converting Enzyme 2Antiviral AgentsPeptidesACE2SARS-CoV-2T-cell epitopesvaccine

Identifiers

PMID36154880
PMCPMC9282900
OpenAlexW4285498117

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.