Evidence map›Paper›PMID 36154691›Full record

ArticleeLife2022

Fat2 polarizes the WAVE complex in

Audrey Miller Williams, Seth Donoughe, Edwin Munro, Sally Horne-Badovinac

Open access · goldAbstract read
In one paragraph

Article in eLife, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 48 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Collective migration modes in development, tissue repair and cancer.Nature reviews. Molecular cell biology · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Atypical Cadherin FAT2 Is Required for Synaptic Integrity and Motor Behaviors.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Finishing the egg.Genetics · 2024
    Article
  18. Cortical tension promotes Kibra degradation via Par-1.Molecular biology of the cell · 2024
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Audrey Miller WilliamsDepartment of Molecular Genetics and Cell Biology, University of Chicago, Chicago, United States.ORCID 0000-0001-6170-3365
Seth DonougheDepartment of Molecular Genetics and Cell Biology, University of Chicago, Chicago, United States.ORCID 0000-0002-4773-5739
Edwin MunroDepartment of Molecular Genetics and Cell Biology, University of Chicago, Chicago, United States.
Sally Horne-BadovinacDepartment of Molecular Genetics and Cell Biology, University of Chicago, Chicago, United States.ORCID 0000-0002-0473-7451
University of Chicago · US

Funding

Training Program in Developmental BiologyT32HD055164 · NICHD · UNIVERSITY OF CHICAGO · PI Sally Horne-Badovinac, Paschalis Kratsios · 2008 to 2026
$3.6M
Mechanisms of epithelial migration and basement membrane assemblyR35GM148285 · NIGMS · UNIVERSITY OF CHICAGO · PI Sally Horne-Badovinac · 2023 to 2026
$2.4M
Mechanistic origins and dynamic control of epithelial zippering and neural tube closureR01HD088831 · NICHD · UNIVERSITY OF CHICAGO · PI MUNRO, EDWIN MARSHALL · 2016 to 2020
$1.6M
Mechanisms that Coordinate Cellular Movements for Epithelial MigrationR01GM126047 · NIGMS · UNIVERSITY OF CHICAGO · PI HORNE-BADOVINAC, SALLY · 2018 to 2021
$1.6M
NICHD NIH HHS R01 HD088831NICHD NIH HHS T32 HD055164NIGMS NIH HHS R01 GM126047NIGMS NIH HHS R35 GM148285
6 · The paper itself

Abstract

For a group of cells to migrate together, each cell must couple the polarity of its migratory machinery with that of the other cells in the cohort. Although collective cell migrations are common in animal development, little is known about how protrusions are coherently polarized among groups of migrating epithelial cells. We address this problem in the collective migration of the follicular epithelial cells in

Indexed as

Drosophila melanogasterDrosophila ProteinsActinsAnimalsCadherinsCell MovementActinsCadherinsDrosophila Proteinsactincell biologycollective cell migrationdevelopmental biologyD. melanogasterepitheliumFat2lamellipodiumWAVE regulatory complex

Identifiers

PMID36154691
PMCPMC9576270
OpenAlexW4297225312

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.