Evidence map›Paper›PMID 36154544›Full record

Trial reportSports health

Effects of Moderate-Intensity Training Under Cyclic Hypoxia on Cardiorespiratory Fitness and Hematological Parameters in People Recovered From COVID-19: The AEROBICOVID Study.

Carlos Dellavechia de Carvalho, Danilo Rodrigues Bertucci, Felipe Alves Ribeiro, Gabriel Peinado Costa, Diana Mota Toro, Marta Camacho-Cardenosa, Javier Brazo-Sayavera, Carlos Arterio Sorgi, Marcelo Papoti, Átila Alexandre Trapé

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Sports health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Rehabilitation and COVID-19: systematic review by Cochrane Rehabilitation.European journal of physical and rehabilitation medicine · 2023
    Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Carlos Dellavechia de Carvalho
Danilo Rodrigues Bertucci
Felipe Alves Ribeiro
Gabriel Peinado Costa
Diana Mota Toro
Marta Camacho-Cardenosa
Javier Brazo-Sayavera
Carlos Arterio Sorgi
Marcelo Papoti
Átila Alexandre Trapé

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRecent studies have indicated that people who live at altitude have a lower incidence of coronavirus disease (COVID-19) and lesser severity in infection cases. HYPOTHESIS: Hypoxia exposure could lead to health benefits, and it could be used in the recovery process as an additional stimulus to physical training to improve cardiorespiratory fitness (CRF). STUDY

designRandomized controlled clinical trial. LEVEL OF EVIDENCE: Level 2.

methodsThe 43 participants, aged 30 to 69 years, were divided into control group (CG, n = 18) and 2 training groups: normoxia (NG, n = 9) and hypoxia (HG, n = 16). Before and after the intervention were evaluated the lactate threshold 2 (L2), peak oxygen uptake (VO

resultsThe 8-week intervention promoted a similar improvement in CRF of people recovered from COVID-19 in the HG (L2 = 34.6%; VO

conclusionThe results of the present study provide evidence that moderate-intensity training in normoxia or hypoxia promoted similar benefits in CRF of people recovered from COVID-19. Furthermore, the hypoxia offered an additional stimulus to training promoting erythropoietin increase and hematological stimulation. CLINICAL RELEVANCE: The present exercise protocol can be used for the rehabilitation of people recovered from COVID-19, with persistent low CRF. In addition, this is the first study demonstrating that physical training combined with hypoxia, as well as improving CRF, promotes greater hematological stimulation in people recovered from COVID-19.

Indexed as

Cardiorespiratory FitnessCOVID-19ErythropoietinAdultAgedHumansHypoxiaMiddle AgedOxygenErythropoietinOxygenaerobic capacityaerobic poweraltitudecoronaviruserythropoietin

Identifiers

PMID36154544
PMCPMC10291297
OpenAlexW4297154133

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.