Evidence map›Paper›PMID 36154019›Full record

ArticleBiochemistry2022

Binding Interface and Electron Transfer Between Nicotine Oxidoreductase and Its Cytochrome c Electron Acceptor.

Elizabeth J Mumby, Jamin A Willoughby, Cristian Vasquez, Niusha Delavari, Zhiyao Zhang, Christopher T Clark, Frederick Stull

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biochemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. DNA-Regulated Multi-Protein Complement Control.Journal of the American Chemical Society · 2024
    Article
  3. FhlA is a Formate Binding Protein.bioRxiv : the preprint server for biology · 2024
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Elizabeth J MumbyDepartment of Chemistry, Western Michigan University, Kalamazoo, Michigan 49008, United States.
Jamin A WilloughbyDepartment of Chemistry, Western Michigan University, Kalamazoo, Michigan 49008, United States.
Cristian VasquezDepartment of Chemistry, Western Michigan University, Kalamazoo, Michigan 49008, United States.
Niusha DelavariDepartment of Chemistry, Western Michigan University, Kalamazoo, Michigan 49008, United States.
Zhiyao ZhangDepartment of Chemistry, Western Michigan University, Kalamazoo, Michigan 49008, United States.
Christopher T ClarkDepartment of Chemistry, Western Michigan University, Kalamazoo, Michigan 49008, United States.
Frederick StullDepartment of Chemistry, Western Michigan University, Kalamazoo, Michigan 49008, United States.ORCID 0000-0002-2969-4224
Western Michigan University · US

Funding

Mechanistic basis for the low O2-dependent activity of a nicotine-degrading enzymeR15GM139069 · NIGMS · WESTERN MICHIGAN UNIVERSITY · PI STULL, FREDERICK · 2021 to 2021
$449k
NIGMS NIH HHS R15 GM139069
6 · The paper itself

Abstract

The enzyme nicotine oxidoreductase (NicA2) is a member of the flavoprotein amine oxidase family that uses a cytochrome c protein (CycN) as its oxidant instead of dioxygen, which is the oxidant used by most other members of this enzyme family. We recently identified a potential binding site for CycN on the surface of NicA2 through rigid body docking [

Indexed as

NicotineOxidoreductasesAminesAmino AcidsCytochromes cElectronsElectron TransportFlavinsFlavoproteinsHemeOxidantsOxidation-ReductionOxygenAminesAmino AcidsCytochromes cFlavinsFlavoproteinsHemeNicotineOxidantsOxidoreductasesOxygen

Identifiers

PMID36154019
PMCPMC10163435
OpenAlexW4297265541

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.