SynthesisJournal of orthopaedic surgery and research2022
Unicompartmental knee arthroplasty is associated with lower pain levels but inferior range of motion, compared with high tibial osteotomy: a systematic overview of meta-analyses.
Synthesis in Journal of orthopaedic surgery and research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 18 citations in OpenAlex.
- The Optimal Dose, Efficacy and Safety of Tranexamic Acid on Hemorrhage Control for High Tibial Osteotomy: A Network Meta-Analysis.Orthopaedic surgery · 2025Pooled it
- Comparison of Unicompartmental Knee Arthroplasty Versus High Tibial Osteotomy for Medial Knee Osteoarthritis: An Updated Meta-Analysis of 56,000 Patients.Orthopaedic surgery · 2025Pooled it
- Short-term outcomes after hybrid unicompartmental knee arthroplasty: A retrospective cohort study with minimum 3-year follow-up.Medicine · 2026Article
- Forgetting the knee after high tibial osteotomy versus unicompartmental knee arthroplasty.BMC musculoskeletal disorders · 2026Article
- SIMULTANEOUS CONTRALATERAL HIGH TIBIAL OSTEOTOMY DURING TOTAL KNEE ARTHROPLASTY: A NEW PERSPECTIVE IN ORTHOPEDIC SURGERY.Orthopedic reviews · 2026Article
- Clinical outcomes of unicompartmental knee arthroplasty in early osteoarthritis without bone-on-bone contact.Archives of orthopaedic and trauma surgery · 2025Article
- High Tibial Osteotomy (HTO), Unicompartmental Knee Arthroplasty (UKA), and Proximal Fibular Osteotomy (PFO) for Medial-Compartment Knee Osteoarthritis: A Narrative Review of Comparative Mechanisms, Clinical Outcomes, and Decision-Making.Journal of clinical medicine · 2025Review
- Hidden blood loss and its risk factors between high tibial osteotomy and unicompartmental knee arthroplasty for knee osteoarthritis: a retrospective study.BMC musculoskeletal disorders · 2025Article
- Spacer-type tibial osteotomy versus open wedge high tibial osteotomy and unicompartmental knee arthroplasty for Kellgren-Lawrence grade 3-4 medial unicompartmental knee osteoarthritis in patients younger than 65 years.Journal of orthopaedic surgery and research · 2025Article
- Opening wedge high tibial osteotomy yields comparable to superior outcomes to unicompartmental knee arthroplasty at 2 years of follow-up in patients suffering from Ahlbäck III knee osteoarthritis: A propensity score-matched analysis.Journal of experimental orthopaedics · 2024Article
- Age-stratified analysis of HTO and UKA clinical effects in cross-indicated anterior medial osteoarthritis.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2024Article
- High tibial osteotomy versus unicompartmental knee arthroplasty for Kellgren-Lawrence grade 3-4 knee osteoarthritis in younger patients: comparable improvements in patient-reported outcomes, adjusted for osteoarthritis grade and sex.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2023Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundThe purpose of this study was to overview the findings of reported meta-analyses on unicompartmental knee arthroplasty (UKA) and high tibial osteotomy (HTO).
methodsThe Preferred Reporting Items for Systematic Reviews and Meta-Analysis 2020 (PRISMA 2020) guidelines were followed. Two independent reviewers conducted a literature search of PubMed, Embase, the Web of Science, and the Cochrane Database of Systematic Reviews for meta-analyses comparing UKA and HTO that were published prior to September 2021. Literature screening, data extraction, and article quality appraisal were performed according to the study protocol registered online at PROSPERO (CRD42021279152).
resultsA total of 10 meta-analyses were identified, and different studies reported different results. Five of the seven meta-analyses showed that the proportion of subjects with excellent or good functional results was higher for UKA than for HTO. All three meta-analyses showed that UKA was associated with lower pain levels, and all six of the studies that included an analysis of range of motion (ROM) reported that UKA was inferior to HTO. Four of the eight meta-analyses found that total complication rates were lower for UKA. Only 3 of the 10 meta-analyses found that UKA had lower revision rates. Moreover, in the subgroup analysis, the revision and complication rates of UKA were similar to those of opening-wedge HTO but much lower than those of closing-wedge HTO.
conclusionsCompared to HTO, UKA was associated with lower pain levels but inferior postoperative ROM. The results were inconclusive regarding whether UKA yielded better knee function scores and lower revision or complication rates than HTO. Accurate identification of indications and appropriate patient selection are essential for treating individuals with OA.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.