Evidence map›Paper›PMID 36153525›Full record

Trial reportBMC pulmonary medicine2022

A pragmatic randomised controlled trial of tailored pulmonary rehabilitation in participants with difficult-to-control asthma and elevated body mass index.

Helen Clare Ricketts, Varun Sharma, Femke Steffensen, Anna Goodfellow, Elaine Mackay, Gordon MacDonald, Duncan S Buchan, Rekha Chaudhuri, Douglas C Cowan

Registry-linked trialOpen access · goldAbstract readPragmatic Clinical TrialRandomized Controlled Trial
In one paragraph

Trial report in BMC pulmonary medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03630432 (A Pragmatic, Randomised, Controlled, Trial of the Effect of a Tailored Pulmonary Rehabilitation Package in Uncontrolled Asthma Associated With Elevated Body Mass Index), which is not on this map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03630432 naunknown statusnot on this map

A Pragmatic, Randomised, Controlled, Trial of the Effect of a Tailored Pulmonary Rehabilitation Package in Uncontrolled Asthma Associated With Elevated Body Mass Index

TypeinterventionalSponsorNHS Greater Glasgow and ClydeRan2017 to 2019Enrolled180ConditionsAsthmaArmsPulmonary rehabilitation, Usual Care
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Patient-centred outcomes in severe asthma: fatigue, sleep, physical activity and work.European respiratory review : an official journal of the European Respiratory Society · 2025
    Review
  6. Review
  7. Protected characteristics reported in pulmonary rehabilitation: a scoping review.European respiratory review : an official journal of the European Respiratory Society · 2024
    Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Helen Clare RickettsCollege of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.
Varun SharmaCollege of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.
Femke SteffensenGlasgow Clinical Research Facility, Glasgow Royal Infirmary, Glasgow, UK.
Anna GoodfellowGlasgow Clinical Research Facility, Glasgow Royal Infirmary, Glasgow, UK.
Elaine MackayPulmonary Rehabilitation Team, Glasgow Royal Infirmary, Glasgow, UK.
Gordon MacDonaldRespiratory Department, 4th Floor, Walton Building, Glasgow Royal Infirmary, 84 Castle Street, Glasgow, G4 0SD, UK.
Duncan S BuchanDivision of Sports and Exercise, University of the West of Scotland, Lanarkshire, UK.
Rekha ChaudhuriInstitute of Infection, Inflammation and Immunity, University of Glasgow, Glasgow, UK.
Douglas C CowanRespiratory Department, 4th Floor, Walton Building, Glasgow Royal Infirmary, 84 Castle Street, Glasgow, G4 0SD, UK. douglas.cowan@ggc.scot.nhs.uk.ORCID http://orcid.org/0000-0001-7297-9041
Glasgow Royal Infirmary · GBUniversity of Glasgow · GBNHS Lanarkshire · GB

Funding

NHS Greater Glasgow and Clyde CG0435 North Glasgow Lung Research Endowment Fund
6 · The paper itself

Abstract

backgroundDifficult-to-control asthma associated with elevated body mass index (BMI) is challenging with limited treatment options. The effects of pulmonary rehabilitation (PR) in this population are uncertain.

methodsThis is a randomised controlled trial of an eight-week asthma-tailored PR programme versus usual care (UC) in participants with difficult-to-control asthma and BMI ≥ 25 kg/m

results95 participants were randomised 1:1 to PR or UC. Median age was 54 years, 60% were female and median BMI was 33.8 kg/m

conclusionsPR improved asthma control and reduced perceived breathlessness in participants with difficult-to-control asthma and elevated BMI. However, this format appears to be suboptimal for this population with high drop-out rates and prolonged time to completion. Trial registration Clinicaltrials.gov. ID NCT03630432. Retrospectively registered, submitted May 26th 2017, posted August 14th 2018.

Indexed as

AsthmaQuality of LifeBody Mass IndexDyspneaExercise TherapyFemaleHumansMaleMiddle AgedAsthmaDifficult-to-control asthmaObesityPulmonary rehabilitation

Identifiers

PMID36153525
PMCPMC9509551
OpenAlexW4296970931

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.