Evidence map›Paper›PMID 36153522›Full record

ReviewJournal of nanobiotechnology2022

Application of MOF-based nanotherapeutics in light-mediated cancer diagnosis and therapy.

Dan Zhao, Wang Zhang, Shuang Yu, Si-Lei Xia, Ya-Nan Liu, Guan-Jun Yang

Open access · goldAbstract readReview
In one paragraph

Review in Journal of nanobiotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 59 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. MOF-Ag Nanozyme forInternational journal of nanomedicine · 2026
    Article
  10. Review
  11. Review
  12. Molecules (Basel, Switzerland) · 2025
    Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Dan ZhaoSchool of Marine Science, Ningbo University, Ningbo, 315211, Zhejiang, China. zhaodan2@nbu.edu.cn.
Wang ZhangSchool of Marine Science, Ningbo University, Ningbo, 315211, Zhejiang, China.
Shuang YuDepartment of Food Science and Engineering, Ningbo University, Ningbo, 315211, China.
Si-Lei XiaSchool of Marine Science, Ningbo University, Ningbo, 315211, Zhejiang, China.
Ya-Nan LiuDepartment of Food Science and Engineering, Ningbo University, Ningbo, 315211, China. liuyanan@nbu.edu.cn.
Guan-Jun YangSchool of Marine Science, Ningbo University, Ningbo, 315211, Zhejiang, China. yangguanjun@nbu.edu.cn.
Ningbo University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Light-mediated nanotherapeutics have recently emerged as promising strategies to precisely control the activation of therapeutic reagents and imaging probe both in vitro and in vivo, largely ascribed to their unique properties, including minimally invasive capabilities and high spatiotemporal resolution. Nanoscale metal-organic frameworks (NMOFs), a new family of hybrid materials consisting of metal attachment sites and bridging ligands, have been explored as a new platform for enhanced cancer diagnosis and therapy due to their tunable size, modifiable surface, good biocompatibility, high agent loading and, most significantly, their ability to be preferentially deposited in tumors through enhanced permeability and retention (EPR). Especially the light-driven NMOF-based therapeutic platform, which not only allow for increased laser penetration depth and enhanced targeting, but also enable imaging-guided or combined treatments. This review provides up-to-date developments of NMOF-based therapeutic platforms for cancer treatment with emphasis on light-triggered therapeutic strategies and introduces their advances in cancer diagnosis and therapy in recent years.

Indexed as

Metal-Organic FrameworksNeoplasmsCombined Modality TherapyDrug CarriersHumansDrug CarriersMetal-Organic FrameworksCancer diagnosisLight-mediatedMetal–organic frameworksNanotherapeuticsTherapy

Identifiers

PMID36153522
PMCPMC9509633
OpenAlexW4296935284

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.