Evidence map›Paper›PMID 36153516›Full record

ArticleBMC pulmonary medicine2022

Computer grading of lung disease severity in patients with lymphangioleiomyomatosis referred for transplantation.

Angelo M Taveira-DaSilva, Vissaagan Gopalakrishnan, Jianhua Yao, Marcus Y Chen, Patricia Julien-Williams, Amanda M Jones, Gustavo Pacheco-Rodriguez, Joel Moss

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC pulmonary medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Quantification of Proteus syndrome-associated lung disease.Orphanet journal of rare diseases · 2024
    Article
  3. CT grading of lung disease in lymphangioleiomyomatosis.AJR. American journal of roentgenology · 2012
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Angelo M Taveira-DaSilvaPulmonary Branch, NHLBI, NIH, Building 10, Room 6D05, MSC 1590, Bethesda, MD, 20892-1590, USA.
Vissaagan GopalakrishnanPulmonary Branch, NHLBI, NIH, Building 10, Room 6D05, MSC 1590, Bethesda, MD, 20892-1590, USA.
Jianhua YaoRadiology and Imaging Sciences Department, NIH, Bethesda, MD, 20892, USA.
Marcus Y ChenCardiovascular Branch, NHLBI, NIH, Bethesda, MD, 20892, USA.
Patricia Julien-WilliamsPulmonary Branch, NHLBI, NIH, Building 10, Room 6D05, MSC 1590, Bethesda, MD, 20892-1590, USA.
Amanda M JonesPulmonary Branch, NHLBI, NIH, Building 10, Room 6D05, MSC 1590, Bethesda, MD, 20892-1590, USA.
Gustavo Pacheco-RodriguezPulmonary Branch, NHLBI, NIH, Building 10, Room 6D05, MSC 1590, Bethesda, MD, 20892-1590, USA.
Joel MossPulmonary Branch, NHLBI, NIH, Building 10, Room 6D05, MSC 1590, Bethesda, MD, 20892-1590, USA. mossj@nhlbi.nih.gov.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesLymphangioleiomyomatosis (LAM) patients with severe lung disease may be considered for lung transplantation. Clinical, physiologic, and quality of life data are usually employed for referral. The aim of this study was to determine whether computed tomographic measurement of lung volume occupied by cysts (cyst score) complemented clinical and physiologic data in supporting referral for transplantation.

methodsForty-one patients were studied. Pre-referral clinical data, pulmonary function tests, exercise testing, and high-resolution computed tomography (HRCT) scans were obtained. From HRCT, a computer-aided diagnostic program was employed to calculate cyst scores. These data were compared to those of 41 age-matched LAM patients not referred for lung transplantation.

resultsCyst score, and % predicted FEV

conclusionsLAM patients referred for lung transplantation had nearly 50% of lungs occupied by cysts. Correlations between cyst score and FEV

Indexed as

CystsLung DiseasesLung NeoplasmsLymphangioleiomyomatosisComputersHumansLungQuality of LifeReferral and ConsultationSeverity of Illness IndexCystic lung diseaseHigh resolution computed tomography (HRCT)Lung transplantLymphangioleiomyomatosis (LAM)

Identifiers

PMID36153516
PMCPMC9509628

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.