Evidence map›Paper›PMID 36152913›Full record

ArticleExperimental eye research2022

Decreased outflow facility and Schlemm's canal defects in a mouse model of glaucoma.

Timur A Mavlyutov, Megan S Kuhn, Samer E Bilal, Michael L De Ieso, Anil K Chauhan, W Daniel Stamer, Colleen M McDowell

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Experimental eye research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Timur A MavlyutovDepartment of Ophthalmology and Visual Sciences, University of Wisconsin-Madison, Madison, WI, 53575, USA.
Megan S KuhnDuke Eye Center, Duke University, Durham, NC, USA.
Samer E BilalDepartment of Ophthalmology and Visual Sciences, University of Wisconsin-Madison, Madison, WI, 53575, USA.
Michael L De IesoDuke Eye Center, Duke University, Durham, NC, USA.
Anil K ChauhanDepartment of Internal Medicine, Division of Hematology/Oncology, University of Iowa, Iowa City, IA, USA.
W Daniel StamerDuke Eye Center, Duke University, Durham, NC, USA.
Colleen M McDowellDepartment of Ophthalmology and Visual Sciences, University of Wisconsin-Madison, Madison, WI, 53575, USA. Electronic address: cmmcdowell@wisc.edu.

Funding

VISION RESEARCHP30EY005722 · NEI · DUKE UNIVERSITY · PI Vadim Y Arshavsky · 1985 to 2026
$19.3M
UW Vision Research Core - Administrative CoreP30EY016665 · NEI · UNIVERSITY OF WISCONSIN-MADISON · PI Donna M Peters · 2005 to 2026
$12.6M
eNOS-Dependent Mechanoregulation of Intraocular PressureR01EY022359 · NEI · DUKE UNIVERSITY · PI STAMER, W DANIEL · 2012 to 2025
$5.6M
Caveolae-Based Mechanosensors for Conventional Outflow RegulationR01EY028608 · NEI · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI MICHAEL H ELLIOTT, W Daniel Stamer · 2018 to 2026
$3.8M
Cross-talk of TGFβ2 and TLR4 in the trabecular meshworkR01EY026529 · NEI · UNIVERSITY OF WISCONSIN-MADISON · PI MCDOWELL, COLLEEN MARY · 2016 to 2022
$2.7M
NEI NIH HHS P30 EY005722NEI NIH HHS P30 EY016665NEI NIH HHS R01 EY022359NEI NIH HHS R01 EY026529NEI NIH HHS R01 EY028608
6 · The paper itself

Abstract

Previously we identified B6.EDA

Indexed as

GlaucomaTrabecular MeshworkAnimalsAqueous HumorDisease Models, AnimalIntraocular PressureMiceMice, Inbred C57BLScleraFN-EDAIOPOcular hypertensionOutflow facilityVE-Cadherin

Identifiers

PMID36152913
PMCPMC9722577

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.